The molecular machinery behind lysosome biogenesis and the maintenance of the perinuclear
aggregate of late endocytic structures is not well understood. A likely candidate for being …

We review and report here the genotypes and phenotypes of 60 novel thalassemia and
abnormal hemoglobin (Hb) mutations discovered following the adoption of routine DNA …

To assess the diagnostic efficacy of T1-weighted magnetic resonance (MR) images when
findings on radiographs of the hip are indeterminate, 20 patients with suspected hip fracture …

OBJECTIVES: The aim of this study was to update the incidence data of beta thalassaemia
mutations in various populations and compare it to the spectrum of mutations in the United …

The beneficial impact of supportive housing on hospital recidivism and employment of former
psychiatric patients has been documented(1-4). However, outcome evaluations have not …

Surface plasmon resonance (SPR) is an extensively used technique to characterize antigen-antibody
interactions. Affinity measurements by SPR typically involve testing the binding of …

We prospectively identified 12 patients who had a shelf at the margin of the placenta consistent
with the diagnosis of circumvallate placenta. Ten patients were followed to delivery and …

Large deletions of the β-globin gene cluster are problematic to diagnose, and consequently
the frequency and range of these mutations in the UK is unknown. Here we present a study …

This paper reports the findings of an evaluation of supportive housing for people who have
been hospitalized in psychiatric facilities. Both qualitative and quantitative methods were …

Background In order to better understand complex diseases, it is important to understand how
genetic variation in the regulatory regions affects gene expression. Genetic variants found …