Background The COVID-19 pandemic is caused by the betacoronavirus SARS-CoV-2. In
November 2021, the Omicron variant was discovered and immediately classified as a variant of …

The novel betacoronavirus severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2)
causes a form of severe pneumonia disease called coronavirus disease 2019 (COVID-19). …

Antibodies are essential tools for therapy and diagnostics. Yet, production remains expensive
as it is mostly done in mammalian expression systems. As most therapeutic IgG require …

The novel betacoranavirus SARS-CoV-2 causes a form of severe pneumonia disease, termed
COVID-19 (coronavirus disease 2019). Recombinant human antibodies are proven potent …

Mpro, also known as 3CLpro, is the main protease of the SARS-CoV-2 coronavirus and, as
such, is essential for the viral life cycle. Two studies have each screened and ranked in silico …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes Coronavirus
disease 2019 (COVID-19) exhibits two major variants based on mutations of its spike protein, …

Background Interleukin-12 is an important cytokine in mediating cellular immune responses.
Results Recombinant single-chain canine IL-12 was produced in a baculovirus-insect cell …

… Contact interfaces have also been investigated by Argos4 and Janin et aL5 Argos found,
in agreement with our observations, that the hydropathy of the average interface lies between …

Th17 cells have never been explored in human graft-versus-host disease (GVHD). We studied
the correlation between the presence of Th17 cells with histologic and clinical parameters…

Cancers are heterogeneous at the cell level, and the mechanisms leading to cancer heterogeneity
could be clonal evolution or cancer stem cells. Cancer stem cells are resistant to most …