Autoregulation of E-cadherin expression by cadherin–cadherin interactions: the roles of β-catenin signaling, Slug, and MAPK
…, I Simcha, T Ben-Yedidia, J Blechman… - The Journal of cell …, 2003 - rupress.org
Transcriptional repression of E-cadherin, characteristic of epithelial to mesenchymal
transition, is often found also during tumor cell invasion. At metastases, migratory fibroblasts …
transition, is often found also during tumor cell invasion. At metastases, migratory fibroblasts …
Dynamic sorting of nuclear components into distinct nucleolar caps during transcriptional inhibition
Y Shav-Tal, J Blechman, X Darzacq… - Molecular biology of …, 2005 - Am Soc Cell Biol
Nucleolar segregation is observed under some physiological conditions of transcriptional
arrest. This process can be mimicked by transcriptional arrest after actinomycin D treatment …
arrest. This process can be mimicked by transcriptional arrest after actinomycin D treatment …
Upregulation of Meis1 and HoxA9 in acute lymphocytic leukemias with the t (4: 11) abnormality
T Rozovskaia, E Feinstein, O Mor, R Foa, J Blechman… - Oncogene, 2001 - nature.com
Rearrangements of the human ALL-1 gene are frequently encountered in acute lymphocytic
leukemias (ALL) and acute myeloid leukemias (AML). These rearrangements are mostly …
leukemias (ALL) and acute myeloid leukemias (AML). These rearrangements are mostly …
The C-terminal SET domains of ALL-1 and TRITHORAX interact with the INI1 and SNR1 proteins, components of the SWI/SNF complex
The ALL-1 gene was discovered by virtue of its involvement in human acute leukemia. Its
Drosophila homolog trithorax (trx) is a member of the trx-Polycomb gene family, which …
Drosophila homolog trithorax (trx) is a member of the trx-Polycomb gene family, which …
[HTML][HTML] Alternative splicing of the pituitary adenylate cyclase-activating polypeptide receptor PAC1: mechanisms of fine tuning of brain activity
J Blechman, G Levkowitz - Frontiers in endocrinology, 2013 - frontiersin.org
Alternative splicing of the precursor mRNA encoding for the neuropeptide receptor PAC1/ADCYAP1R1
generates multiple protein products that exhibit pleiotropic activities. Recent …
generates multiple protein products that exhibit pleiotropic activities. Recent …
The fourth immunoglobulin domain of the stem cell factor receptor couples ligand binding to signal transduction
JM Blechman, S Lev, J Barg, M Eisenstein, B Vaks… - Cell, 1995 - cell.com
Receptor dimerization is ubiquitous to the action of all receptor tyrosine kinases, and in the
case of dimeric ligands, such as the stem cell factor (SCF), it was attributed to ligand bivalency…
case of dimeric ligands, such as the stem cell factor (SCF), it was attributed to ligand bivalency…
huASH1 protein, a putative transcription factor encoded by a human homologue of the Drosophila ash1 gene, localizes to both nuclei and cell–cell tight junctions
T Nakamura, J Blechman, S Tada… - Proceedings of the …, 2000 - National Acad Sciences
During animal development, regions of the embryo become committed to position-specific
identities, which are determined by spatially restricted expression of Hox/homeotic genes. …
identities, which are determined by spatially restricted expression of Hox/homeotic genes. …
Steel factor and c-kit protooncogene: genetic lessons in signal transduction
S Lev, JM Blechman, D Givol… - Critical Reviews™ in …, 1994 - dl.begellhouse.com
Despite extensive research on the molecular mechanisms of signal transduction by growth
factors and their oncogenic receptor tyrosine kinases, the physiological relevance of these …
factors and their oncogenic receptor tyrosine kinases, the physiological relevance of these …
Nuclear punctate distribution of ALL-1 is conferred by distinct elements at the N terminus of the protein
T Yano, T Nakamura, J Blechman… - Proceedings of the …, 1997 - National Acad Sciences
The ALL-1 gene positioned at 11q23 is directly involved in human acute leukemia either
through a variety of chromosome translocations or by partial tandem duplications. ALL-1 is the …
through a variety of chromosome translocations or by partial tandem duplications. ALL-1 is the …
Specification of hypothalamic neurons by dual regulation of the homeodomain protein Orthopedia
J Blechman, N Borodovsky, M Eisenberg… - 2007 - journals.biologists.com
In the developing hypothalamus, a variety of neurons are generated adjacent to each other
in a highly coordinated, but poorly understood process. A critical question that remains …
in a highly coordinated, but poorly understood process. A critical question that remains …