User profiles for Japinder Nijjer
Japinder NijjerSenior Scientist, AstraZeneca Verified email at yale.edu Cited by 279 |
Morphogenesis and cell ordering in confined bacterial biofilms
Biofilms are aggregates of bacterial cells surrounded by an extracellular matrix. Much progress
has been made in studying biofilm growth on solid substrates; however, little is known …
has been made in studying biofilm growth on solid substrates; however, little is known …
The dynamics of miscible viscous fingering from onset to shutdown
We examine the full ‘life cycle’ of miscible viscous fingering from onset to shutdown with the
aid of high-resolution numerical simulations. We study the injection of one fluid into a planar …
aid of high-resolution numerical simulations. We study the injection of one fluid into a planar …
Stable and unstable miscible displacements in layered porous media
The effect of permeability heterogeneities and viscosity variations on miscible displacement
processes in porous media is examined using high-resolution numerical simulations and …
processes in porous media is examined using high-resolution numerical simulations and …
Bacteria surfing the elastic wave
Elasticity-driven synchronization in active solids has been predicted theoretically and was
recently realized in a synthetic system. A biological realization is now demonstrated in a …
recently realized in a synthetic system. A biological realization is now demonstrated in a …
[HTML][HTML] Vibrio cholerae biofilms use modular adhesins with glycan-targeting and nonspecific surface binding domains for colonization
Bacterial biofilms are formed on environmental surfaces and host tissues, and facilitate host
colonization and antibiotic resistance by human pathogens. Bacteria often express multiple …
colonization and antibiotic resistance by human pathogens. Bacteria often express multiple …
[HTML][HTML] Mechanical forces drive a reorientation cascade leading to biofilm self-patterning
In growing active matter systems, a large collection of engineered or living autonomous units
metabolize free energy and create order at different length scales as they proliferate and …
metabolize free energy and create order at different length scales as they proliferate and …
Biofilms as self-shaping growing nematics
Active nematics are the non-equilibrium analogue of passive liquid crystals. They consist of
anisotropic units that consume free energy to drive emergent behaviour. As with liquid crystal …
anisotropic units that consume free energy to drive emergent behaviour. As with liquid crystal …
Flow-induced compaction of a deformable porous medium
Fluid flowing through a deformable porous medium imparts viscous drag on the solid matrix,
causing it to deform. This effect is investigated theoretically and experimentally in a one-…
causing it to deform. This effect is investigated theoretically and experimentally in a one-…
Mechanical resilience of biofilms toward environmental perturbations mediated by extracellular matrix
Biofilms are surface‐associated communities of bacterial cells embedded in an extracellular
matrix (ECM). Biofilm cells can survive and thrive in various dynamic environments causing …
matrix (ECM). Biofilm cells can survive and thrive in various dynamic environments causing …
[HTML][HTML] Lipoarabinomannan mediates localized cell wall integrity during division in mycobacteria
The growth and division of mycobacteria, which include clinically relevant pathogens,
deviate from that of canonical bacterial models. Despite their Gram-positive ancestry, …
deviate from that of canonical bacterial models. Despite their Gram-positive ancestry, …