As plastic waste accumulates in the ocean at alarming rates, the need for efficient and
sustainable remediation solutions is urgent. One solution is the development and mobilization of …

Epithelial‐to‐mesenchymal transition ( EMT ) and its reverse mesenchymal‐to‐epithelial
transition ( MET ) have been suggested to play crucial roles in metastatic dissemination of …

PURPOSE Androgen receptor splice variant 7 (AR-V7) results in a truncated receptor,
which leads to ligand-independent constitutive activation that is not inhibited by anti-androgen …

Cancer metastasis and therapy resistance are the major unsolved clinical challenges, and
account for nearly all cancer-related deaths. Both metastasis and therapy resistance are …

Metastasis is a significant contributor to morbidity and mortality for many cancer patients and
remains a major obstacle for effective treatment. In many tissue types, metastasis is fueled …

ATRX is one of the most frequently altered genes in solid tumors, and mutation is especially
frequent in soft tissue sarcomas. However, the role of ATRX in tumor development and …

Metastatic dissemination requires carcinoma cells to detach from the primary tumor and invade
through the basement membrane. To acquire these characteristics, epithelial tumor cells …

Phenotypic plasticity involves a process in which cells transiently acquire phenotypic traits
of another lineage. Two commonly studied types of phenotypic plasticity are epithelial-…

Background Historically, amputation was the primary surgical treatment for osteosarcoma of
the extremities; however, with advancements in surgical techniques and chemotherapies …

Alternative splicing is a general mechanism for regulating gene expression that affects the
RNA products of more than 90% of human genes. Not surprisingly, alternative splicing is …