Nuclear factor kappa B (NF-κB) transcription factors are evolutionarily conserved, coordinating
regulators of immune and inflammatory responses. They also play a pivotal role in …

Tuned and distinct responses of macrophages and dendritic cells to Toll-like receptor 4 (TLR4)
activation induced by lipopolysaccharide (LPS) underpin the balance between innate …

Background The worst Ebola virus disease (EVD) outbreak in history has resulted in more
than 28,000 cases and 11,000 deaths. We present the final results of two phase 1 trials of an …

Study Design Predictive correlational study. Objectives To identify the incidence of medial
tibial stress syndrome (MTSS) in a group of high school cross-country runners and to …

Primaquine is used to eradicate the hepatic or hypnozoite form of Plasmodium vivax that
may lead to relapse of infection. Host genetic factors may play a role in the activity of …

Background. Three full doses of RTS,S/AS01 malaria vaccine provides partial protection
against controlled human malaria parasite infection (CHMI) and natural exposure. Immunization …

Aims This prospective, randomized, multicenter trial evaluated the 6‐month success rate of
sacral neuromodulation (SNM) with InterStim® Therapy versus standard medical therapy (…

Alzheimer's disease (AD) is characterized by the deposition in brain of β‐amyloid (Aβ) peptides,
elevated brain caspase‐3, and systemic deficiency of cytochrome c oxidase. Although …

Background The efficacy of the 8-aminoquinoline (8AQ) drug primaquine (PQ) has been
historically linked to CYP-mediated metabolism. Although to date no clear evidence exists in the …

Ultrasound (US) has become a ubiquitous technological process in a large variety of
scientific disciplines. However, little information exists on the use of ultrasound to enhance …