[HTML][HTML] Clinical use of whole genome sequencing for Mycobacterium tuberculosis
Drug-resistant tuberculosis (TB) remains a major challenge to global health and to healthcare
in the UK. In 2014, a total of 6,520 cases of TB were recorded in England, of which 1.4 % …
in the UK. In 2014, a total of 6,520 cases of TB were recorded in England, of which 1.4 % …
[HTML][HTML] Cytological and transcript analyses reveal fat and lazy persister-like bacilli in tuberculous sputum
…, SM Lee, RJ Smith, C Senner, J Hinds… - PLoS …, 2008 - journals.plos.org
Background Tuberculous sputum provides a sample of bacilli that must be eliminated by
chemotherapy and that may go on to transmit infection. A preliminary observation that …
chemotherapy and that may go on to transmit infection. A preliminary observation that …
[HTML][HTML] Pneumococcal carriage in vaccine-eligible children and unvaccinated infants in Lao PDR two years following the introduction of the 13-valent pneumococcal …
…, ML Nation, KK Fox, CD Nguyen, KA Gould, J Hinds… - Vaccine, 2019 - Elsevier
Pneumococcal carriage is a prerequisite for disease, and underpins herd protection provided
by pneumococcal conjugate vaccines (PCVs). There are few data on the impact of PCVs in …
by pneumococcal conjugate vaccines (PCVs). There are few data on the impact of PCVs in …
Microarrays Reveal that Each of the Ten Dominant Lineages of Staphylococcus aureus Has a Unique Combination of Surface-Associated and Regulatory Genes
…, RA Stabler, SE Husain, PD Butcher, J Hinds - Journal of …, 2006 - Am Soc Microbiol
Staphylococcus aureus is the most common cause of hospital-acquired infection. In healthy
hosts outside of the health care setting, S. aureus is a frequent colonizer of the human nose …
hosts outside of the health care setting, S. aureus is a frequent colonizer of the human nose …
Dissection of the heat-shock response in Mycobacterium tuberculosis using mutants and microarrays
…, L Wernisch, R Stabler, JA Mangan, J Hinds… - …, 2002 - microbiologyresearch.org
Regulation of the expression of heat-shock proteins plays an important role in the pathogenesis
of Mycobacterium tuberculosis. The heat-shock response of bacteria involves genome-…
of Mycobacterium tuberculosis. The heat-shock response of bacteria involves genome-…
Dissection of ESAT-6 System 1 of Mycobacterium tuberculosis and Impact on Immunogenicity and Virulence
…, MI De Jonge, D Bottai, C Demangel, J Hinds… - Infection and …, 2006 - Am Soc Microbiol
The dedicated secretion system ESX-1 of Mycobacterium tuberculosis encoded by the
extended RD1 region (extRD1) assures export of the ESAT-6 protein and its partner, the 10-kDa …
extended RD1 region (extRD1) assures export of the ESAT-6 protein and its partner, the 10-kDa …
Whole genome comparison of Campylobacter jejuni human isolates using a low-cost microarray reveals extensive genetic diversity
N Dorrell, JA Mangan, KG Laing, J Hinds… - Genome …, 2001 - genome.cshlp.org
Campylobacter jejuni is the leading cause of bacterial food-borne diarrhoeal disease
throughout the world, and yet is still a poorly understood pathogen. Whole genome microarray …
throughout the world, and yet is still a poorly understood pathogen. Whole genome microarray …
A member of the cAMP receptor protein family of transcription regulators in Mycobacterium tuberculosis is required for virulence in mice and controls transcription of …
…, MC Menéndez, R Whalan, J Hinds… - Molecular …, 2005 - Wiley Online Library
Deletion of gene Rv3676 in Mycobacterium tuberculosis coding for a transcription factor
belonging to the cAMP receptor protein (CRP) family caused growth defects in laboratory …
belonging to the cAMP receptor protein (CRP) family caused growth defects in laboratory …
Gene expression profile of Mycobacterium tuberculosis in a non-replicating state
DGN Muttucumaru, G Roberts, J Hinds, RA Stabler… - Tuberculosis, 2004 - Elsevier
Mycobacterium tuberculosis is able to persist in the human host for decades in an apparently
dormant state where it is presumed to reside in an hypoxic environment. This can be …
dormant state where it is presumed to reside in an hypoxic environment. This can be …
Stationary phase gene expression of Mycobacterium tuberculosis following a progressive nutrient depletion: a model for persistent organisms?
T Hampshire, S Soneji, J Bacon, BW James, J Hinds… - Tuberculosis, 2004 - Elsevier
The majority of individuals infected with TB develop a latent infection, in which organisms
survive within the body while evading the host immune system. Such persistent bacilli are …
survive within the body while evading the host immune system. Such persistent bacilli are …