User profiles for Jason Town
Jason P TownUniversity of California San Francisco Verified email at ucsf.edu Cited by 240 |
Carbon dots for carbon dummies: the quantum and the molecular questions among some others
R de Boëver, JR Town, X Li… - Chemistry–A European …, 2022 - Wiley Online Library
Carbon Dots (CDs) are carbon nanoparticles which were discovered in 2004. Despite two
decades of intensive work from the scientific community and a colossal amount of gathered …
decades of intensive work from the scientific community and a colossal amount of gathered …
[PDF][PDF] Cell protrusions and contractions generate long-range membrane tension propagation
Membrane tension is thought to be a long-range integrator of cell physiology. Membrane
tension has been proposed to enable cell polarity during migration through front-back …
tension has been proposed to enable cell polarity during migration through front-back …
The WAVE complex associates with sites of saddle membrane curvature
A Pipathsouk, RM Brunetti, JP Town… - Journal of Cell …, 2021 - rupress.org
How local interactions of actin regulators yield large-scale organization of cell shape and
movement is not well understood. Here we investigate how the WAVE complex organizes sheet…
movement is not well understood. Here we investigate how the WAVE complex organizes sheet…
[HTML][HTML] Cell confinement reveals a branched-actin independent circuit for neutrophil polarity
Migratory cells use distinct motility modes to navigate different microenvironments, but it is
unclear whether these modes rely on the same core set of polarity components. To investigate …
unclear whether these modes rely on the same core set of polarity components. To investigate …
Mechanosensitive mTORC2 independently coordinates leading and trailing edge polarity programs during neutrophil migration
By acting both upstream of and downstream from biochemical organizers of the cytoskeleton,
physical forces function as central integrators of cell shape and movement. Here we use a …
physical forces function as central integrators of cell shape and movement. Here we use a …
State-of-the-art cooling technology for a turbine rotor blade
J Town, D Straub, J Black… - Journal of …, 2018 - asmedigitalcollection.asme.org
Effective internal and external cooling of airfoils is key to maintaining component life for
efficient gas turbines. Cooling designs have spanned the range from simple internal convective …
efficient gas turbines. Cooling designs have spanned the range from simple internal convective …
A toolkit for rapid modular construction of biological circuits in mammalian cells
The ability to rapidly assemble and prototype cellular circuits is vital for biological research
and its applications in biotechnology and medicine. Current methods for the assembly of …
and its applications in biotechnology and medicine. Current methods for the assembly of …
Progressive enhancement of kinetic proofreading in T cell antigen discrimination from receptor activation to DAG generation
T cells use kinetic proofreading to discriminate antigens by converting small changes in
antigen-binding lifetime into large differences in cell activation, but where in the signaling …
antigen-binding lifetime into large differences in cell activation, but where in the signaling …
[HTML][HTML] Local negative feedback of Rac activity at the leading edge underlies a pilot pseudopod-like program for amoeboid cell guidance
To migrate efficiently, neutrophils must polarize their cytoskeletal regulators along a single
axis of motion. This polarization process is thought to be mediated through local positive …
axis of motion. This polarization process is thought to be mediated through local positive …
Actin-driven protrusions generate rapid long-range membrane tension propagation in cells
Membrane tension is thought to be a long-range integrator of cell physiology. This role
necessitates effective tension transmission across the cell. However, the field remains strongly …
necessitates effective tension transmission across the cell. However, the field remains strongly …