Diagnostic pathology is the foundation and gold standard for identifying carcinomas. However,
high inter-observer variability substantially affects productivity in routine pathology and is …

Sarcomatoid change has been well documented in the various subtypes of renal cell
carcinoma (RCC) and its presence is known to portend a worse prognosis in RCC. Mucinous …

Background Tumours rapidly ferment glucose to lactic acid even in the presence of oxygen,
and coupling high glycolysis with poor perfusion leads to extracellular acidification. We …

Urachal carcinoma is a rare tumor that has not been well studied. To determine the pathologic
and clinical features of this disease, we retrospectively evaluated 46 cases from our …

These results suggest that macrophage-targeted therapies can be combined with androgen
deprivation therapy to treat patients with prostate cancer by limiting cholesterol …

The identification of new and effective therapeutic targets for the lethal, castration-resistant
stage of prostate cancer (CRPC) has been challenging because of both the paucity of …

Answer questions and earn CME/CNE Squamous cell carcinoma (SCC) of the penis is a rare
malignancy in the United States, with a significantly higher incidence—up to 20 to 30 times …

Background Penile squamous cell carcinoma (PSCC) is a rare malignancy, and those patients
with metastatic disease have limited treatment options. Treatment is largely comprised of …

Background Personalized genomic classifiers have transformed the management of
prostate cancer (PCa) by identifying the most aggressive subsets of PCa. Nevertheless, the …

Thyroid-like follicular carcinoma of the kidney is an extremely rare variant of renal cell
carcinoma. Most previously reported cases presented as incidental small tumors confined to the …