User profiles for Jastyn A. Pöpplau

Jastyn Poepplau

Institute of Developmental Neurophysiology, University Medical Center Hamburg-Eppendorf …
Verified email at zmnh.uni-hamburg.de
Cited by 283

[PDF][PDF] A transient developmental increase in prefrontal activity alters network maturation and causes cognitive dysfunction in adult mice

SH Bitzenhofer, JA Pöpplau, M Chini, A Marquardt… - Neuron, 2021 - cell.com
Disturbed neuronal activity in neuropsychiatric pathologies emerges during development and
might cause multifold neuronal dysfunction by interfering with apoptosis, dendritic growth, …

[PDF][PDF] Resolving and rescuing developmental miswiring in a mouse model of cognitive impairment

M Chini, JA Pöpplau, C Lindemann, L Carol-Perdiguer… - Neuron, 2020 - cell.com
Cognitive deficits, core features of mental illness, largely result from dysfunction of prefrontal
networks. This dysfunction emerges during early development, before a detectable …

[HTML][HTML] Anesthetics fragment hippocampal network activity, alter spine dynamics, and affect memory consolidation

W Yang, M Chini, JA Pöpplau, A Formozov… - PLoS …, 2021 - journals.plos.org
General anesthesia is characterized by reversible loss of consciousness accompanied by
transient amnesia. Yet, long-term memory impairment is an undesirable side effect. How …

[HTML][HTML] Tapered fibers combined with a multi-electrode array for optogenetics in mouse medial prefrontal cortex

…, SH Bitzenhofer, B Spagnolo, JA Pöpplau… - Frontiers in …, 2018 - frontiersin.org
Optogenetics offers many advantages in terms of cell-type specificity, allowing to investigate
functional connectivity between different brain areas at high spatial and neural population …

[HTML][HTML] Neural correlates of anesthesia in newborn mice and humans

M Chini, S Gretenkord, JK Kostka, JA Pöpplau… - Frontiers in neural …, 2019 - frontiersin.org
Pöpplau 1 , Laura Cornelissen 2,3 , Charles B. Berde 2,3 , Ileana L. Hanganu-Opatz 1*† …
Citation: Chini M, Gretenkord S, Kostka JK, Pöpplau JA, Cornelissen L, Berde CB, Hanganu-…

Gamma activity accelerates during prefrontal development

SH Bitzenhofer, JA Pöpplau, I Hanganu-Opatz - elife, 2020 - elifesciences.org
Gamma oscillations are a prominent activity pattern in the cerebral cortex. While gamma
rhythms have been extensively studied in the adult prefrontal cortex in the context of cognitive (…

[PDF][PDF] Reorganization of adolescent prefrontal cortex circuitry is required for mouse cognitive maturation

JA Pöpplau, T Schwarze, M Dorofeikova, I Pochinok… - Neuron, 2024 - cell.com
Most cognitive functions involving the prefrontal cortex emerge during late development.
Increasing evidence links this delayed maturation to the protracted timeline of prefrontal …

[HTML][HTML] Calcium Imaging and Electrophysiology of hippocampal Activity under Anesthesia and natural Sleep in Mice

A Formozov, M Chini, A Dieter, W Yang, JA Pöpplau… - Scientific Data, 2022 - nature.com
The acute effects of anesthesia and their underlying mechanisms are still not fully understood.
Thus, comprehensive analysis and efficient generalization require their description in …

[PDF][PDF] Activity-dependent maturation of prefrontal gamma oscillations sculpts cognitive performance

SH Bitzenhofer, JA Pöpplau, M Chini, A Marquardt… - BioRxiv, 2019 - researchgate.net
Activity-dependent maturation of prefrontal gamma oscillations sculpts cognitive performance
Page 1 Gamma control of cognitive maturation Bitzenhofer et al. 1 1 2 3 4 5 6 7 …

Microglia inhibition rescues developmental hypofrontality in a mouse model of mental illness

M Chini, C Lindemann, JA Pöpplau, X Xu, J Ahlbeck… - bioRxiv, 2018 - biorxiv.org
Cognitive deficits, core features of mental illness, largely result from dysfunction of prefrontal-hippocampal
networks. This dysfunction emerges already during early development, before …