User profiles for Jastyn A. Pöpplau
Jastyn PoepplauInstitute of Developmental Neurophysiology, University Medical Center Hamburg-Eppendorf … Verified email at zmnh.uni-hamburg.de Cited by 283 |
[PDF][PDF] A transient developmental increase in prefrontal activity alters network maturation and causes cognitive dysfunction in adult mice
Disturbed neuronal activity in neuropsychiatric pathologies emerges during development and
might cause multifold neuronal dysfunction by interfering with apoptosis, dendritic growth, …
might cause multifold neuronal dysfunction by interfering with apoptosis, dendritic growth, …
[PDF][PDF] Resolving and rescuing developmental miswiring in a mouse model of cognitive impairment
M Chini, JA Pöpplau, C Lindemann, L Carol-Perdiguer… - Neuron, 2020 - cell.com
Cognitive deficits, core features of mental illness, largely result from dysfunction of prefrontal
networks. This dysfunction emerges during early development, before a detectable …
networks. This dysfunction emerges during early development, before a detectable …
[HTML][HTML] Anesthetics fragment hippocampal network activity, alter spine dynamics, and affect memory consolidation
General anesthesia is characterized by reversible loss of consciousness accompanied by
transient amnesia. Yet, long-term memory impairment is an undesirable side effect. How …
transient amnesia. Yet, long-term memory impairment is an undesirable side effect. How …
[HTML][HTML] Tapered fibers combined with a multi-electrode array for optogenetics in mouse medial prefrontal cortex
…, SH Bitzenhofer, B Spagnolo, JA Pöpplau… - Frontiers in …, 2018 - frontiersin.org
Optogenetics offers many advantages in terms of cell-type specificity, allowing to investigate
functional connectivity between different brain areas at high spatial and neural population …
functional connectivity between different brain areas at high spatial and neural population …
[HTML][HTML] Neural correlates of anesthesia in newborn mice and humans
M Chini, S Gretenkord, JK Kostka, JA Pöpplau… - Frontiers in neural …, 2019 - frontiersin.org
… Pöpplau 1 , Laura Cornelissen 2,3 , Charles B. Berde 2,3 , Ileana L. Hanganu-Opatz 1*† …
Citation: Chini M, Gretenkord S, Kostka JK, Pöpplau JA, Cornelissen L, Berde CB, Hanganu-…
Citation: Chini M, Gretenkord S, Kostka JK, Pöpplau JA, Cornelissen L, Berde CB, Hanganu-…
Gamma activity accelerates during prefrontal development
Gamma oscillations are a prominent activity pattern in the cerebral cortex. While gamma
rhythms have been extensively studied in the adult prefrontal cortex in the context of cognitive (…
rhythms have been extensively studied in the adult prefrontal cortex in the context of cognitive (…
[PDF][PDF] Reorganization of adolescent prefrontal cortex circuitry is required for mouse cognitive maturation
JA Pöpplau, T Schwarze, M Dorofeikova, I Pochinok… - Neuron, 2024 - cell.com
Most cognitive functions involving the prefrontal cortex emerge during late development.
Increasing evidence links this delayed maturation to the protracted timeline of prefrontal …
Increasing evidence links this delayed maturation to the protracted timeline of prefrontal …
[HTML][HTML] Calcium Imaging and Electrophysiology of hippocampal Activity under Anesthesia and natural Sleep in Mice
The acute effects of anesthesia and their underlying mechanisms are still not fully understood.
Thus, comprehensive analysis and efficient generalization require their description in …
Thus, comprehensive analysis and efficient generalization require their description in …
[PDF][PDF] Activity-dependent maturation of prefrontal gamma oscillations sculpts cognitive performance
SH Bitzenhofer, JA Pöpplau, M Chini, A Marquardt… - BioRxiv, 2019 - researchgate.net
Activity-dependent maturation of prefrontal gamma oscillations sculpts cognitive performance
Page 1 Gamma control of cognitive maturation Bitzenhofer et al. 1 1 2 3 4 5 6 7 …
Page 1 Gamma control of cognitive maturation Bitzenhofer et al. 1 1 2 3 4 5 6 7 …
Microglia inhibition rescues developmental hypofrontality in a mouse model of mental illness
M Chini, C Lindemann, JA Pöpplau, X Xu, J Ahlbeck… - bioRxiv, 2018 - biorxiv.org
Cognitive deficits, core features of mental illness, largely result from dysfunction of prefrontal-hippocampal
networks. This dysfunction emerges already during early development, before …
networks. This dysfunction emerges already during early development, before …