A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers

…, H Davies, PT Simpson, Y Li, X Zou, J Diez-Perez… - Nature …, 2017 - nature.com
Somatic rearrangements contribute to the mutagenized landscape of cancer genomes. Here,
we systematically interrogated rearrangements in 560 breast cancers by using a piecewise …

CentrosomeDB: a human centrosomal proteins database

…, F Abascal, J Díez-Pérez… - Nucleic acids …, 2009 - academic.oup.com
Active research on the biology of the centrosome during the past decades has allowed the
identification and characterization of many centrosomal proteins. Unfortunately, the …

[HTML][HTML] Apolipoprotein L2 contains a BH3-like domain but it does not behave as a BH3-only protein

…, R Iurlaro, N El Mjiyad, J Díez-Pérez… - Cell death & …, 2014 - nature.com
Apolipoproteins of the L family are lipid-binding proteins whose function is largely unknown.
Apolipoprotein L1 and apolipoprotein L6 have been recently described as novel pro-death …

[HTML][HTML] Drug repurposing based on a quantum-inspired method versus classical fingerprinting uncovers potential antivirals against SARS-CoV-2

…, JI Diaz-Hernandez, J Diez Perez… - PLoS computational …, 2022 - journals.plos.org
The COVID-19 pandemic has accelerated the need to identify new antiviral therapeutics at
pace, including through drug repurposing. We employed a Quadratic Unbounded Binary …

Promoters of ASCL1‐and NEUROD1‐dependent genes are specific targets of lurbinectedin in SCLC cells

…, CM Genes Robles, J Diez Perez… - EMBO Molecular …, 2022 - embopress.org
Small‐Cell Lung Cancer (SCLC) is an aggressive neuroendocrine malignancy with a poor
prognosis. Here, we focus on the neuroendocrine SCLC subtypes, SCLC‐A and SCLC‐N, …

Corrigendum: A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers

…, H Davies, PT Simpson, Y Li, X Zou, J Diez-Perez… - Nature …, 2017 - go.gale.com
In the version of this article initially published online, in the Methods section, under
subheading" Rearrangement signatures," the statement" Putative regions of clustered …

FOrMAT: Feasibility of a molecular characterization approach to treatment of patients (pts) with advanced gastrointestinal (GI) tumors.

…, BA Walker, S Hulkki Wilson, J Diez Perez… - 2015 - ascopubs.org
TPS227 Background: The molecular characteristics of a pt’s tumour can determine their
suitability for treatment with targeted drugs. Several molecular alterations are only seen in a …

Estrategias en el juego motor reglado y desarrollo del pensamiento táctico en un grupo de Educación Primaria

CJ Díez Pérez - 2016 - uvadoc.uva.es
En la elaboración del presente TFG he pretendido plasmar la importancia del pensamiento
táctico, introduciendo en el aula una nueva metodología alternativa a la existente, …

Drug repurposing based on a quantum-inspired method versus classical fingerprinting uncovers potential antivirals against SARS-CoV-2: Quantum-inspired …

…, JI Diaz-Hernandez, JD Perez… - PLoS Computational …, 2022 - kclpure.kcl.ac.uk
The COVID-19 pandemic has accelerated the need to identify new antiviral therapeutics at
pace, including through drug repurposing. We employed a Quadratic Unbounded Binary …

Drug repurposing based on a Quantum-Inspired method versus classical fingerprinting uncovers potential antivirals against SARS-CoV-2 including vitamin B12 …

BM Moreno, JID Hernandez, JD Perez, AM Playa… - 2021 - pesquisa.bvsalud.org
The COVID-19 pandemic has accelerated the need to identify new therapeutics at pace,
including through drug repurposing. We employed a Quadratic Unbounded Binary Optimization …