User profiles for Javier Gayán

Javier Gayan

Roche
Verified email at roche.com
Cited by 5133

The trans-ancestral genomic architecture of glycemic traits

…, Q Duan, J Engmann, SA Fatumo, J Gayán… - Nature …, 2021 - nature.com
Glycemic traits are used to diagnose and monitor type 2 diabetes and cardiometabolic health.
To date, most genetic studies of glycemic traits have focused on individuals of European …

Independent genome-wide scans identify a chromosome 18 quantitative-trait locus influencing dyslexia

…, AJ Richardson, JB Talcott, J Gayán… - Nature …, 2002 - nature.com
Developmental dyslexia is defined as a specific and significant impairment in reading ability
that cannot be explained by deficits in intelligence, learning opportunity, motivation or …

[PDF][PDF] Quantitative-trait locus for specific language and reading deficits on chromosome 6p

J Gayán, SD Smith, SS Cherny, LR Cardon… - The American Journal of …, 1999 - cell.com
Reading disability (RD), or dyslexia, is a complex cognitive disorder manifested by difficulties
in learning to read, in otherwise normal individuals. Individuals with RD manifest deficits in …

Genetic and environmental influences on orthographic and phonological skills in children with reading disabilities

J Gayán, RK Olson - Developmental neuropsychology, 2001 - Taylor & Francis
Data from identical and fraternal twins were analyzed to estimate the proportions of genetic
and environmental influences on group deficits in accuracy and, when available, speed for …

Genetic and environmental influences on individual differences in printed word recognition

J Gayán, RK Olson - Journal of experimental child psychology, 2003 - Elsevier
… , and orthographic coding found by Gayán and Olson mirror those found for genetic correlations
for individual differences in these variables. The results from Gayán and Olson and the …

[HTML][HTML] Multiple Sclerosis Risk Variant HLA-DRB1*1501 Associates with High Expression of DRB1 Gene in Different Human Populations

…, D Ndagire, A Catala-Rabasa, A Ruiz, J Gayan… - PloS one, 2012 - journals.plos.org
The human leukocyte antigen (HLA) DRB1*1501 has been consistently associated with
multiple sclerosis (MS) in nearly all populations tested. This points to a specific antigen …

Quantitative trait locus for reading disability on chromosome 6p is pleiotropic for attention‐deficit/hyperactivity disorder

…, SD Smith, LR Cardon, J Gayán… - American Journal of …, 2002 - Wiley Online Library
Comorbidity is pervasive among both adult and child psychiatric disorders; however, the
etiological mechanisms underlying the majority of comorbidities are unknown. This study used …

[HTML][HTML] Convergent genetic linkage and associations to language, speech and reading measures in families of probands with specific language impairment

ML Rice, SD Smith, J Gayán - Journal of neurodevelopmental disorders, 2009 - Springer
We analyzed genetic linkage and association of measures of language, speech and reading
phenotypes to candidate regions in a single set of families ascertained for SLI. Sib-pair and …

The relationship between CAG repeat length and age of onset differs for Huntington's disease patients with juvenile onset or adult onset

JM Andresen, J Gayán, L Djoussé… - Annals of human …, 2007 - Wiley Online Library
Age of onset for Huntington's disease (HD) varies inversely with the length of the disease‐causing
CAG repeat expansion in the HD gene. A simple exponential regression model …

[HTML][HTML] The membrane-spanning 4-domains, subfamily A (MS4A) gene cluster contains a common variant associated with Alzheimer's disease

C Antúnez, M Boada, A González-Pérez, J Gayán… - Genome medicine, 2011 - Springer
Background In order to identify novel loci associated with Alzheimer's disease (AD), we
conducted a genome-wide association study (GWAS) in the Spanish population. Methods We …