User profiles for Javier Gayán
Javier GayanRoche Verified email at roche.com Cited by 5133 |
The trans-ancestral genomic architecture of glycemic traits
Glycemic traits are used to diagnose and monitor type 2 diabetes and cardiometabolic health.
To date, most genetic studies of glycemic traits have focused on individuals of European …
To date, most genetic studies of glycemic traits have focused on individuals of European …
Independent genome-wide scans identify a chromosome 18 quantitative-trait locus influencing dyslexia
Developmental dyslexia is defined as a specific and significant impairment in reading ability
that cannot be explained by deficits in intelligence, learning opportunity, motivation or …
that cannot be explained by deficits in intelligence, learning opportunity, motivation or …
[PDF][PDF] Quantitative-trait locus for specific language and reading deficits on chromosome 6p
Reading disability (RD), or dyslexia, is a complex cognitive disorder manifested by difficulties
in learning to read, in otherwise normal individuals. Individuals with RD manifest deficits in …
in learning to read, in otherwise normal individuals. Individuals with RD manifest deficits in …
Genetic and environmental influences on orthographic and phonological skills in children with reading disabilities
Data from identical and fraternal twins were analyzed to estimate the proportions of genetic
and environmental influences on group deficits in accuracy and, when available, speed for …
and environmental influences on group deficits in accuracy and, when available, speed for …
Genetic and environmental influences on individual differences in printed word recognition
… , and orthographic coding found by Gayán and Olson mirror those found for genetic correlations
for individual differences in these variables. The results from Gayán and Olson and the …
for individual differences in these variables. The results from Gayán and Olson and the …
[HTML][HTML] Multiple Sclerosis Risk Variant HLA-DRB1*1501 Associates with High Expression of DRB1 Gene in Different Human Populations
The human leukocyte antigen (HLA) DRB1*1501 has been consistently associated with
multiple sclerosis (MS) in nearly all populations tested. This points to a specific antigen …
multiple sclerosis (MS) in nearly all populations tested. This points to a specific antigen …
Quantitative trait locus for reading disability on chromosome 6p is pleiotropic for attention‐deficit/hyperactivity disorder
Comorbidity is pervasive among both adult and child psychiatric disorders; however, the
etiological mechanisms underlying the majority of comorbidities are unknown. This study used …
etiological mechanisms underlying the majority of comorbidities are unknown. This study used …
[HTML][HTML] Convergent genetic linkage and associations to language, speech and reading measures in families of probands with specific language impairment
ML Rice, SD Smith, J Gayán - Journal of neurodevelopmental disorders, 2009 - Springer
We analyzed genetic linkage and association of measures of language, speech and reading
phenotypes to candidate regions in a single set of families ascertained for SLI. Sib-pair and …
phenotypes to candidate regions in a single set of families ascertained for SLI. Sib-pair and …
The relationship between CAG repeat length and age of onset differs for Huntington's disease patients with juvenile onset or adult onset
JM Andresen, J Gayán, L Djoussé… - Annals of human …, 2007 - Wiley Online Library
Age of onset for Huntington's disease (HD) varies inversely with the length of the disease‐causing
CAG repeat expansion in the HD gene. A simple exponential regression model …
CAG repeat expansion in the HD gene. A simple exponential regression model …
[HTML][HTML] The membrane-spanning 4-domains, subfamily A (MS4A) gene cluster contains a common variant associated with Alzheimer's disease
Background In order to identify novel loci associated with Alzheimer's disease (AD), we
conducted a genome-wide association study (GWAS) in the Spanish population. Methods We …
conducted a genome-wide association study (GWAS) in the Spanish population. Methods We …