User profiles for Jaydeep Sidhaye
 | Jaydeep SidhayeIMBA, Vienna Verified email at imba.oeaw.ac.at Cited by 488 |
Brain organoids: an ensemble of bioassays to investigate human neurodevelopment and disease
J Sidhaye, JA Knoblich - Cell Death & Differentiation, 2021 - nature.com
Understanding etiology of human neurological and psychiatric diseases is challenging.
Genomic changes, protracted development, and histological features unique to human brain …
Genomic changes, protracted development, and histological features unique to human brain …
Concerted action of neuroepithelial basal shrinkage and active epithelial migration ensures efficient optic cup morphogenesis
10.7554/eLife.22689.001 Organ formation is a multi-scale event that involves changes at
the intracellular, cellular and tissue level. Organogenesis often starts with the formation of …
the intracellular, cellular and tissue level. Organogenesis often starts with the formation of …
[PDF][PDF] Interkinetic nuclear migration is centrosome independent and ensures apical cell division to maintain tissue integrity
Pseudostratified epithelia are widespread during animal development and feature elongated
cells whose nuclei adopt various positions along the apicobasal cell axis. Before mitosis, …
cells whose nuclei adopt various positions along the apicobasal cell axis. Before mitosis, …
Integrated transcriptome and proteome analysis reveals posttranscriptional regulation of ribosomal genes in human brain organoids
J Sidhaye, P Trepte, N Sepke, M Novatchkova… - Elife, 2023 - elifesciences.org
During development of the human cerebral cortex, multipotent neural progenitors generate
excitatory neurons and glial cells. Investigations of the transcriptome and epigenome have …
excitatory neurons and glial cells. Investigations of the transcriptome and epigenome have …
[PDF][PDF] Collective cell migration during optic cup formation features changing cell-matrix interactions linked to matrix topology
Cell migration is crucial for organismal development and shapes organisms in health and
disease. Although a lot of research has revealed the role of intracellular components and …
disease. Although a lot of research has revealed the role of intracellular components and …
Using light sheet fluorescence microscopy to image zebrafish eye development
Light sheet fluorescence microscopy (LSFM) is gaining more and more popularity as a method
to image embryonic development. The main advantages of LSFM compared to confocal …
to image embryonic development. The main advantages of LSFM compared to confocal …
Morphogenesis and development of human telencephalic organoids in the absence and presence of exogenous extracellular matrix
The establishment and maintenance of apical‐basal polarity is a fundamental step in brain
development, instructing the organization of neural progenitor cells (NPCs) and the …
development, instructing the organization of neural progenitor cells (NPCs) and the …
[HTML][HTML] The zebrafish goosepimples/myosin Vb mutant exhibits cellular attributes of human microvillus inclusion disease
Microvillus inclusion disease (MVID) is a life-threatening enteropathy characterised by
malabsorption and incapacitating fluid loss due to chronic diarrhoea. Histological analysis has …
malabsorption and incapacitating fluid loss due to chronic diarrhoea. Histological analysis has …
[HTML][HTML] Myosin Vb mediated plasma membrane homeostasis regulates peridermal cell size and maintains tissue homeostasis in the zebrafish epidermis
The epidermis is a stratified epithelium, which forms a barrier to maintain the internal milieu
in metazoans. Being the outermost tissue, growth of the epidermis has to be strictly …
in metazoans. Being the outermost tissue, growth of the epidermis has to be strictly …
Morphogenesis and development of human telencephalic organoids in the absence and presence of exogenous ECM
Establishment and maintenance of apical-basal polarity is a fundamental step in brain
development, instructing the organization of neural progenitor cells (NPCs) and the developing …
development, instructing the organization of neural progenitor cells (NPCs) and the developing …