User profiles for Jaymin Patel

Jaymin Patel

- Verified email at yale.edu - Cited by 1645

Jaymin Patel

- Verified email at cdc.gov - Cited by 1221

Recoded organisms engineered to depend on synthetic amino acids

…, Z Li, MW Grome, BM Gassaway, M Amiram, JR Patel… - Nature, 2015 - nature.com
Genetically modified organisms (GMOs) are increasingly used in research and industrial
systems to produce high-value pharmaceuticals, fuels and chemicals 1 . Genetic isolation and …

[HTML][HTML] Cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids

…, M Amiram, AK Ranji Charna, JR Patel… - Nature …, 2018 - nature.com
Cell-free protein synthesis has emerged as a powerful approach for expanding the range of
genetically encoded chemistry into proteins. Unfortunately, efforts to site-specifically …

[PDF][PDF] Heart disease prediction using machine learning and data mining technique

J Patel, D TejalUpadhyay, S Patel - Heart Disease, 2015 - researchgate.net
Heart disease is the main reason for death in the world over the last decade. Almost one
person dies of Heart disease about every minute in the United States alone. Researchers have …

[PDF][PDF] Germinal center B cell and T follicular helper cell development initiates in the interfollicular zone

SM Kerfoot, G Yaari, JR Patel, KL Johnson… - Immunity, 2011 - cell.com
We identify the interfollicular (IF) zone as the site where germinal center B cell and T follicular
helper (Tfh) cell differentiation initiates. For the first 2 days postimmunization, antigen-…

Multilayered genetic safeguards limit growth of microorganisms to defined environments

RR Gallagher, JR Patel, AL Interiano… - Nucleic acids …, 2015 - academic.oup.com
Genetically modified organisms (GMOs) are commonly used to produce valuable compounds
in closed industrial systems. However, their emerging applications in open clinical or …

Racial disparities in COVID-19 outcomes among black and white patients with cancer

…, MA Fiala, R Monahan, AY Zhou, JM Patel… - JAMA network …, 2022 - jamanetwork.com
Importance Non-Hispanic Black individuals experience a higher burden of COVID-19 than
the general population; hence, there is an urgent need to characterize the unique clinical …

[HTML][HTML] Host iron status and iron supplementation mediate susceptibility to erythrocytic stage Plasmodium falciparum

…, A Fulford, AM Prentice, MA Elnagheeb, J Patel… - Nature …, 2014 - nature.com
Iron deficiency and malaria have similar global distributions, and frequently co-exist in pregnant
women and young children. Where both conditions are prevalent, iron supplementation …

[HTML][HTML] Th-17 cell activation in response to high salt following acute kidney injury is associated with progressive fibrosis and attenuated by AT-1R antagonism

P Mehrotra, JB Patel, CM Ivancic, JA Collett… - Kidney international, 2015 - Elsevier
Exposure of rats to elevated dietary salt following recovery from acute kidney injury (AKI)
accelerates the transition to chronic kidney disease (CKD), and is dependent on lymphocyte …

Synthesis and Antimicrobial Activity of 3-(1, 3, 4-Oxadiazol-2-yl) quinazolin-4 (3H)-ones

NB Patel, JC Patel - Scientia pharmaceutica, 2010 - mdpi.com
In attempt to find new pharmacologically active molecules, we report here the synthesis and
in vitro antimicrobial activity of various 3-(1, 3, 4-oxadiazol-2-yl)-quinazolin-4 (3 H)-ones. …

Repurposing the translation apparatus for synthetic biology

BJ Des Soye, JR Patel, FJ Isaacs, MC Jewett - Current opinion in chemical …, 2015 - Elsevier
Highlights • Non-standard amino acid incorporation expands the repertoire of protein functions.
• Orthogonal translation systems enable site-specific non-standard amino acid insertion. …