In 2016, the order Mononegavirales was emended through the addition of two new families (Mymonaviridae
and Sunviridae), the elevation of the paramyxoviral subfamily …

Vaccine and antiviral development against SARS-CoV-2 infection or COVID-19 disease
would benefit from validated small animal models. Here, we show that transgenic mice …

The tripartite toxin produced by Bacillus anthracis is the key determinant in the etiology of
anthrax. We have engineered a panel of toxin-neutralizing antibodies, including single-chain …

Non-human primate models will expedite therapeutics and vaccines for coronavirus
disease 2019 (COVID-19) to clinical trials. Here, we compare acute severe acute respiratory …

Ribavirin (l-β-d-ribofuranosyl-l,2,4-triazole-3-carboxamide) is a broad-spectrum antiviral
agent whose molecular mode of action remains remarkably controversial. This antiviral agent …

Background The rapid development of effective medical countermeasures against potential
biological threat agents is vital. Repurposing existing drugs that may have unanticipated …

In 2017, the order Mononegavirales was expanded by the inclusion of a total of 69 novel
species. Five new rhabdovirus genera and one new nyamivirus genus were established to …

Highly infectious illness caused by pathogens is endemic especially in developing nations
where there is limited laboratory infrastructure and trained personnel. Rapid point-of-care (…

In 2018, the order Mononegavirales was expanded by inclusion of 1 new genus and 12 novel
species. This article presents the updated taxonomy of the order Mononegavirales as now …

Metagenomic next-generation sequencing (mNGS), the shotgun sequencing of RNA and
DNA from clinical samples, has proved useful for broad-spectrum pathogen detection and the …