The genetic architecture of the human cerebral cortex
…, PR Schofield, R Secolin, CY Shapland, L Shen, J Shin… - Science, 2020 - science.org
INTRODUCTION The cerebral cortex underlies our complex cognitive capabilities.
Variations in human cortical surface area and thickness are associated with neurological, …
Variations in human cortical surface area and thickness are associated with neurological, …
Common genetic variants influence human subcortical brain structures
The highly complex structure of the human brain is strongly shaped by genetic influences 1 .
Subcortical brain regions form circuits with cortical areas to coordinate movement 2 , …
Subcortical brain regions form circuits with cortical areas to coordinate movement 2 , …
Novel genetic loci underlying human intracranial volume identified through genome-wide association
Intracranial volume reflects the maximally attained brain size during development, and remains
stable with loss of tissue in late life. It is highly heritable, but the underlying genes remain …
stable with loss of tissue in late life. It is highly heritable, but the underlying genes remain …
Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation
Characterizing genetic influences on DNA methylation (DNAm) provides an opportunity to
understand mechanisms underpinning gene regulation and disease. In the present study, we …
understand mechanisms underpinning gene regulation and disease. In the present study, we …
Graduate students of color: Race, racism, and mentoring in the white waters of academia
…, DG Embrick, JH Shin - Sociology of race and …, 2017 - journals.sagepub.com
The graduate student experience, for many, can be a time of great stress, insecurity, and
uncertainty. Overwhelmingly, studies verify that good mentoring is one of the best indicators of …
uncertainty. Overwhelmingly, studies verify that good mentoring is one of the best indicators of …
[HTML][HTML] Novel genetic loci associated with hippocampal volume
The hippocampal formation is a brain structure integrally involved in episodic memory, spatial
navigation, cognition and stress responsiveness. Structural abnormalities in hippocampal …
navigation, cognition and stress responsiveness. Structural abnormalities in hippocampal …
Prenatal exposure to maternal cigarette smoking and DNA methylation: epigenome-wide association in a discovery sample of adolescents and replication in an …
Background: Prenatal exposure to maternal cigarette smoking (prenatal smoke exposure)
had been associated with altered DNA methylation (DNAm) at birth. Objective: We examined …
had been associated with altered DNA methylation (DNAm) at birth. Objective: We examined …
Genetic architecture of subcortical brain structures in 38,851 individuals
…, E Walton, D Tordesillas-Gutierrez, GE Davies, J Shin… - Nature …, 2019 - nature.com
Subcortical brain structures are integral to motion, consciousness, emotions and learning.
We identified common genetic variation related to the volumes of the nucleus accumbens, …
We identified common genetic variation related to the volumes of the nucleus accumbens, …
Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function
…, H Prokisch, W Rathmann, M Roden, S Sebert, J Shin… - Nature …, 2022 - nature.com
We determined the relationships between DNA sequence variation and DNA methylation
using blood samples from 3,799 Europeans and 3,195 South Asians. We identify 11,165,559 …
using blood samples from 3,799 Europeans and 3,195 South Asians. We identify 11,165,559 …
[HTML][HTML] Genome-wide association study of lifetime cannabis use based on a large meta-analytic sample of 32 330 subjects from the International Cannabis …
…, V Richarte, RJ Rose, J Shin… - Translational …, 2016 - nature.com
Cannabis is the most widely produced and consumed illicit psychoactive substance worldwide.
Occasional cannabis use can progress to frequent use, abuse and dependence with all …
Occasional cannabis use can progress to frequent use, abuse and dependence with all …