User profiles for Jean-Pierre Timmermans

Jean-Pierre Timmermans

Full Professor, Cell biology & HIstology, University of Antwerp
Verified email at uantwerpen.be
Cited by 17159

Disrupted function and axonal distribution of mutant tyrosyl-tRNA synthetase in dominant intermediate Charcot-Marie-Tooth neuropathy

…, P Callaerts, L Van Den Bosch, JP Timmermans… - Nature …, 2006 - nature.com
Charcot-Marie-Tooth (CMT) neuropathies are common disorders of the peripheral nervous
system caused by demyelination or axonal degeneration, or a combination of both features. …

The dissection course–necessary and indispensable for teaching anatomy to medical students

HW Korf, H Wicht, RL Snipes, JP Timmermans… - Annals of Anatomy …, 2008 - Elsevier
Anatomy is a major basic subject in medicine and related biomedical sciences. A central
tool most universities use for teaching anatomy is the “dissection course”, in which medical …

In Vitro Susceptibilities of Leishmania donovani Promastigote and Amastigote Stages to Antileishmanial Reference Drugs: Practical Relevance of Stage-Specific …

…, RI da Luz, K Toté, JP Timmermans… - Antimicrobial agents …, 2009 - Am Soc Microbiol
The in vitro susceptibilities of the reference strain Leishmania donovani MHOM/ET/67/L82
to sodium stibogluconate, amphotericin B, miltefosine, and the experimental compound PX-…

Insufficient activation of autophagy allows cellular damage to accumulate in critically ill patients

…, F Güiza, W Martinet, JP Timmermans… - The Journal of …, 2011 - academic.oup.com
Context: Responses to critical illness, such as excessive inflammation and hyperglycemia,
may trigger detrimental chain reactions that damage cellular proteins and organelles. Such …

[HTML][HTML] Involvement of PLEKHM1 in osteoclastic vesicular transport and osteopetrosis in incisors absent rats and humans

…, E Van Hul, JP Timmermans… - The Journal of …, 2007 - Am Soc Clin Investig
This study illustrates that Plekhm1 is an essential protein for bone resorption, as loss-of-function
mutations were found to underlie the osteopetrotic phenotype of the incisors absent rat …

Selective clearance of macrophages in atherosclerotic plaques by autophagy

…, MWM Knaapen, K Salu, JP Timmermans… - Journal of the American …, 2007 - jacc.org
Objectives : The purpose of this study was to investigate whether stent-based delivery of an
inhibitor of mammalian target of rapamycin (mTOR) can selectively clear macrophages in …

Purinergic signaling in the airways

…, I Brouns, D Adriaensen, JP Timmermans - Pharmacological …, 2012 - ASPET
Evidence for a significant role and impact of purinergic signaling in normal and diseased
airways is now beyond dispute. The present review intends to provide the current state of …

[HTML][HTML] A globin in the nucleus!

…, D Flamez, S Dewilde, JP Timmermans… - Journal of Biological …, 2003 - ASBMB
Cytoglobin and neuroglobin are recently discovered members of the globin family. In situ
hybridization localized neuroglobin mainly in brain and retina, while cytoglobin was expressed …

Outer submucous plexus: an intrinsic nerve network involved in both secretory and motility processes in the intestine of large mammals and humans

JP Timmermans, J Hens… - The Anatomical Record …, 2001 - Wiley Online Library
The architecture of the enteric nerve networks in the gastrointestinal tract appears to be more
complex in large mammals, including humans, than in small laboratory animals. At least …

Structural organization and neuropeptide distribution in the mammalian enteric nervous system, with special attention to those components involved in mucosal …

JP Timmermans, D Adriaensen, W Cornelissen… - … and Physiology Part A …, 1997 - Elsevier
Gastrointestinal events such as peristalsis and secretion/absorption processes are influenced
by the enteric nervous system, which is capable of acting largely independently from other …