Intelligence is highly heritable 1 and a major determinant of human health and well-being 2
. Recent genome-wide meta-analyses have identified 24 genomic loci linked to variation in …

Objective Little is known about the longitudinal genetic and environmental association
between juvenile irritability and symptoms of anxiety and depression. This study’s goal was to …

Neuroticism is an important risk factor for psychiatric traits, including depression 1 , anxiety 2
, 3 , and schizophrenia 4 , 5 – 6 . At the time of analysis, previous genome-wide association …

Background In the US, Latino and Asian American immigrants and ethnic minorities may be
at increased risk for alcohol and drug use disorders (AUDs/DUDs). The role of psychosocial …

Alzheimer’s disease (AD) is highly heritable and recent studies have identified over 20
disease-associated genomic loci. Yet these only explain a small proportion of the genetic …

Late-onset Alzheimer’s disease is a prevalent age-related polygenic disease that accounts
for 50–70% of dementia cases. Currently, only a fraction of the genetic variants underlying …

Insomnia is the second most prevalent mental disorder, with no sufficient treatment available.
Despite substantial heritability, insight into the associated genes and neurobiological …

Insomnia is a heritable, highly prevalent sleep disorder for which no sufficient treatment
currently exists. Previous genome-wide association studies with up to 1.3 million subjects …

Schizophrenia (SCZ) and bipolar disorder (BD) are severe mental disorders associated with
cognitive impairment, which is considered a major determinant of functional outcome. …

Background Several typologies have proposed two etiological pathways involved in the
development of alcohol misuse which are associated with the internalizing and externalizing …