User profiles for Jeeyun Chung
Jeeyun ChungHarvard University Verified email at fas.harvard.edu Cited by 2095 |
[PDF][PDF] LDAF1 and seipin form a lipid droplet assembly complex
Lipid droplets (LDs) originate from the endoplasmic reticulum (ER) to store triacylglycerol (TG)
and cholesterol esters. The ER protein seipin was shown to localize to ER-LD contacts …
and cholesterol esters. The ER protein seipin was shown to localize to ER-LD contacts …
PI4P/phosphatidylserine countertransport at ORP5-and ORP8-mediated ER–plasma membrane contacts
Lipid transfer between cell membrane bilayers at contacts between the endoplasmic reticulum
(ER) and other membranes help to maintain membrane lipid homeostasis. We found that …
(ER) and other membranes help to maintain membrane lipid homeostasis. We found that …
An open-access volume electron microscopy atlas of whole cells and tissues
…, S Takemura, Z Lu, HA Pasolli, N Iyer, J Chung… - Nature, 2021 - nature.com
Understanding cellular architecture is essential for understanding biology. Electron
microscopy (EM) uniquely visualizes cellular structures with nanometre resolution. However, …
microscopy (EM) uniquely visualizes cellular structures with nanometre resolution. However, …
Lipid droplet biogenesis
TC Walther, J Chung… - Annual review of cell and …, 2017 - annualreviews.org
Lipid droplets (LDs) are ubiquitous organelles that store neutral lipids for energy or
membrane synthesis and act as hubs for metabolic processes. Cells generate LDs de novo, …
membrane synthesis and act as hubs for metabolic processes. Cells generate LDs de novo, …
Seipin transmembrane segments critically function in triglyceride nucleation and lipid droplet budding from the membrane
Lipid droplets (LDs) are organelles formed in the endoplasmic reticulum (ER) to store
triacylglycerol (TG) and sterol esters. The ER protein seipin is key for LD biogenesis. Seipin forms …
triacylglycerol (TG) and sterol esters. The ER protein seipin is key for LD biogenesis. Seipin forms …
PtdIns4P synthesis by PI4KIIIα at the plasma membrane and its impact on plasma membrane identity
Plasma membrane phosphatidylinositol (PI) 4-phosphate (PtdIns4P) has critical functions via
both direct interactions and metabolic conversion to PI 4,5-bisphosphate (PtdIns(4,5)P 2 ) …
both direct interactions and metabolic conversion to PI 4,5-bisphosphate (PtdIns(4,5)P 2 ) …
Nanoscale subcellular architecture revealed by multicolor three-dimensional salvaged fluorescence imaging
…, LK Schroeder, MD Lessard, P Kidd, J Chung… - Nature …, 2020 - nature.com
Combining the molecular specificity of fluorescent probes with three-dimensional imaging at
nanoscale resolution is critical for investigating the spatial organization and interactions of …
nanoscale resolution is critical for investigating the spatial organization and interactions of …
Nuclear import of hTERT requires a bipartite nuclear localization signal and Akt-mediated phosphorylation
Sustained cell proliferation requires telomerase to maintain functional telomeres that are
essential for chromosome integrity and protection. Although nuclear import of telomerase …
essential for chromosome integrity and protection. Although nuclear import of telomerase …
Plasticity of PI 4 KIII α interactions at the plasma membrane
Plasma membrane PI 4P is an important direct regulator of many processes that occur at the
plasma membrane and also a biosynthetic precursor of PI (4,5)P 2 and its downstream …
plasma membrane and also a biosynthetic precursor of PI (4,5)P 2 and its downstream …
[HTML][HTML] The Troyer syndrome protein spartin mediates selective autophagy of lipid droplets
Lipid droplets (LDs) are crucial organelles for energy storage and lipid homeostasis.
Autophagy of LDs is an important pathway for their catabolism, but the molecular mechanisms …
Autophagy of LDs is an important pathway for their catabolism, but the molecular mechanisms …