User profiles for Jeffrey Law

Jeffrey Law

National Renewable Energy Lab
Verified email at nrel.gov
Cited by 669

Benchmarking algorithms for gene regulatory network inference from single-cell transcriptomic data

A Pratapa, AP Jalihal, JN Law, A Bharadwaj… - Nature methods, 2020 - nature.com
We present a systematic evaluation of state-of-the-art algorithms for inferring gene regulatory
networks from single-cell transcriptional data. As the ground truth for assessing accuracy, …

[HTML][HTML] GPR54 (KISS1R) transactivates EGFR to promote breast cancer cell invasiveness

M Zajac, J Law, DD Cvetkovic, M Pampillo, L McColl… - PloS one, 2011 - journals.plos.org
Kisspeptins (Kp), peptide products of the Kisspeptin-1 (KISS1) gene are endogenous ligands
for a G protein-coupled receptor 54 (GPR54). Previous findings have shown that KISS1 …

[HTML][HTML] Multi-objective goal-directed optimization of de novo stable organic radicals for aqueous redox flow batteries

SS SV, JN Law, CE Tripp, D Duplyakin… - Nature Machine …, 2022 - nature.com
Advances in the field of goal-directed molecular optimization offer the promise of finding
feasible candidates for even the most challenging molecular design applications. One example …

[PS][PS] In-Kernel Servers on Mach 3.0: Implementation and Performance.

J Lepreau, M Hibler, B Ford, J Law, DB Orr - USENIX MACH Symposium, 1993 - usenix.org
The advantages in modularity and power of microkernel-based operating systems such as
Mach 3.0 are well known. The existing performance problems of these systems, however, are …

A note on Jeffrey conditionalization

H Field - Philosophy of Science, 1978 - cambridge.org
… this last equation with Jeffrey's law (3) we would get a law of the form (2). In … Jeffrey's law
(3) with an input law is to reparameterize it, using an input parameter in place of q. And Jeffrey

Recycling waste materials in geopolymer concrete

A Mohajerani, D Suter, T Jeffrey-Bailey, T Song… - Clean Technologies and …, 2019 - Springer
The widespread industry adoption of geopolymer concrete has the potential to positively
contribute to environmental sustainability in both the industrial and construction sectors, through …

The dramatic presentation of colonic lipomata: report of two cases and review of the literature

JM Franc-Law, LR Begin, CA Vasilevsky… - The American …, 2001 - journals.sagepub.com
Colonic lipoma with a dramatic presentation requiring urgent operation is a rare occurrence.
We report two such cases in conjunction with a review of the literature on colonic lipomata. …

A potent anti-CD70 antibody–drug conjugate combining a dimeric pyrrolobenzodiazepine drug with site-specific conjugation technology

SC Jeffrey, PJ Burke, RP Lyon, DW Meyer… - Bioconjugate …, 2013 - ACS Publications
A highly cytotoxic DNA cross-linking pyrrolobenzodiazepine (PBD) dimer with a valine-alanine
dipeptide linker was conjugated to the anti-CD70 h1F6 mAb either through endogenous …

Deconstructing public participation in the Water Framework Directive: implementation and compliance with the letter or with the spirit of the law?

PA Ker Rault, PJ Jeffrey - Water and Environment Journal, 2008 - Wiley Online Library
This article offers a fresh reading of the Water Framework Directive (WFD) and of the Common
Implementation Strategy guidance document number 8 on public participation (PP) aimed …

Development of orally active inhibitors of protein and cellular fucosylation

…, SC Jeffrey, K Klussman, CL Law… - Proceedings of the …, 2013 - National Acad Sciences
The key role played by fucose in glycoprotein and cellular function has prompted significant
research toward identifying recombinant and biochemical strategies for blocking its …