Background Weight gain and weight loss are associated with changes in blood pressure
through unknown mechanisms. Central melanocortinergic signaling is implicated in the control …

The semi-enclosed nature of the Mediterranean Sea, together with its smaller inertia due to
the relative short residence time of its water masses, make it highly reactive to external …

Clinically relevant subtypes exist for pancreatic ductal adenocarcinoma (PDAC), but molecular
characterization is not yet standard in clinical care. We implemented a biopsy protocol to …

A natural Bayesian approach for mixture models with an unknown number of components is
to take the usual finite mixture model with symmetric Dirichlet weights, and put a prior on the …

The standard approach to Bayesian inference is based on the assumption that the distribution
of the data belongs to the chosen model class. However, even a small violation of this …

OBJECTIVE Inflammation is associated with pancreatic β-cell apoptosis and reduced insulin
sensitivity. Literature suggests that interleukin (IL)-1β may contribute to the pathogenesis of …

For data assumed to come from a finite mixture with an unknown number of components, it
has become common to use Dirichlet process mixtures (DPMs) not only for density estimation…

I. Introduction WITH the advent of synthetic glucocorticoids in the late 1940s, adrenalectomy
ushered in the modern era of treatment for Cushing's syndrome. Nearly two decades later, …

In many applications, a finite mixture is a natural model, but it can be difficult to choose an
appropriate number of components. To circumvent this choice, investigators are increasingly …

Chorus is a small, operationally independent clinical development organization within Eli
Lilly and Company that specializes in drug development from candidate selection to clinical …