User profiles for Jenna E. Haines

Jenna E Haines

University of California Berkeley
Verified email at berkeley.edu
Cited by 1629

Local regulation of gene expression by lncRNA promoters, transcription and splicing

JM Engreitz, JE Haines, EM Perez, G Munson, J Chen… - Nature, 2016 - nature.com
Mammalian genomes are pervasively transcribed 1 , 2 to produce thousands of long non-coding
RNAs (lncRNAs) 3 , 4 . A few of these lncRNAs have been shown to recruit regulatory …

Dense Bicoid hubs accentuate binding along the morphogen gradient

M Mir, A Reimer, JE Haines, XY Li… - Genes & …, 2017 - genesdev.cshlp.org
Morphogen gradients direct the spatial patterning of developing embryos; however, the
mechanisms by which these gradients are interpreted remain elusive. Here we used lattice light-…

ZBTB7A acts as a tumor suppressor through the transcriptional repression of glycolysis

XS Liu, JE Haines, EK Mehanna, MD Genet… - Genes & …, 2014 - genesdev.cshlp.org
Elevated glycolysis is a common metabolic trait of cancer, but what drives such metabolic
reprogramming remains incompletely clear. We report here a novel transcriptional repressor-…

Convergence of topological domain boundaries, insulators, and polytene interbands revealed by high-resolution mapping of chromatin contacts in the early …

MR Stadler, JE Haines, MB Eisen - Elife, 2017 - elifesciences.org
10.7554/eLife.29550.001 High-throughput assays of three-dimensional interactions of
chromosomes have shed considerable light on the structure of animal chromatin. Despite this …

[HTML][HTML] Patterns of chromatin accessibility along the anterior-posterior axis in the early Drosophila embryo

JE Haines, MB Eisen - PLoS genetics, 2018 - journals.plos.org
As the Drosophila embryo transitions from the use of maternal RNAs to zygotic transcription,
domains of open chromatin, with relatively low nucleosome density and specific histone …

ZBTB7A suppresses melanoma metastasis by transcriptionally repressing MCAM

XS Liu, MD Genet, JE Haines, EK Mehanna, S Wu… - Molecular Cancer …, 2015 - AACR
The excessive metastatic propensity of melanoma makes it the most deadly form of skin
cancer, yet the underlying mechanism of metastasis remains elusive. Here, mining of cancer …

[PDF][PDF] Neighborhood regulation by lncRNA promoters, transcription, and splicing.

JM Engreitz, JE Haines, G Munson, J Chen, EM Perez… - Bio Rxiv. - core.ac.uk
Mammalian genomes are pervasively transcribed to produce thousands of spliced long
noncoding RNAs (lncRNAs), whose functions remain poorly understood. Because recent …

Spatially uniform establishment of chromatin accessibility in the early Drosophila embryo

JE Haines, MB Eisen - bioRxiv, 2017 - biorxiv.org
As the Drosophila embryo transitions from the use of maternal RNAs to zygotic transcription,
domains of open chromatin, with relatively low nucleosome density and specific histone …

[BOOK][B] More than Just on and off: Exploring Enhancer Function and Regulation During Early Embryonic Development

JE Haines - 2020 - search.proquest.com
… Steven Brenner has approved this thesis based on the entirety of the doctoral work of
Jenna Haines, including oral presentations of thesis content; due to an accident injury, he has …

Changes in suspected adverse drug reaction reporting via the yellow card scheme in Wales following the introduction of a National Reporting Indicator

…, K Jones, KE Haines, E Carey… - British Journal of …, 2022 - Wiley Online Library
Aims This study aimed to assess the impact of a National Reporting Indicator (NRI) on rates
of reporting of suspected adverse drug reactions using the Yellow Card scheme following …