Vitrification, not cryoprotectant exposure, alters the expression of developmentally important genes in in vitro produced porcine blastocysts

LK Bartolac, JL Lowe, G Koustas, CG Grupen… - Cryobiology, 2018 - Elsevier
The vitrification of embryos is common practice in advanced livestock breeding programs
and in human fertility clinics. Recent studies have revealed that vitrification results in aberrant …

[HTML][HTML] No evidence for genome editing in mouse zygotes and HEK293T human cell line using the DNA-guided Natronobacterium gregoryi Argonaute (NgAgo)

NC Khin, JL Lowe, LM Jensen, G Burgio - PloS one, 2017 - journals.plos.org
A recently published research article reported that the extreme halophile archaebacterium
Natronobacterium gregoryi Argonaute enzyme (NgAgo) could cleave the cellular DNA under …

Effect of carbohydrates on lipid metabolism during porcine oocyte IVM

JL Lowe, R Bathgate, CG Grupen - Reproduction, Fertility and …, 2019 - CSIRO Publishing
Porcine oocytes contain a large amount of endogenous lipid, which is thought to function as
an intracellular source of energy. The aim of this study was to determine the effects of …

Cryotolerance of porcine blastocysts is improved by treating in vitro matured oocytes with L-carnitine prior to fertilization

JL Lowe, LK Bartolac, R Bathgate… - Journal of Reproduction …, 2017 - jstage.jst.go.jp
Sufficient generation of adenosine triphosphate (ATP) by oocytes is critical for fertilization
and embryo development. The objective of this study was to determine the effects of …

No evidence for genome editing of the endogenous DNA in mouse zygotes and HEK293T human cell line using the DNA-guided Natronobacterium gregoryi …

N Chi Khin, JL Lowe, L Jensen, G Burgio - bioRxiv, 2016 - biorxiv.org
A recently published research article reported that the extreme halophile archaebacterium
Natronobacterium gregoryi Argonaute enzyme (NgAgo) could cleave the cellular DNA under …

Lake benthic algae: toward an understanding of their ecology

M Cantonati, RL Lowe - Freshwater Science, 2014 - journals.uchicago.edu
Lake phytoplankton studies outnumber studies on lake periphyton by an order of magnitude,
and most periphyton research has been done in streams. Most benthic algal taxa found in …

Monkeypox outbreak—Nine states, May 2022: Weekly/June 10, 2022/71 (23); 764–769

…, D Kuhar, M LaFlam, R Lash, A Lashombe, D Lowe… - 2022 - Wiley Online Library
PCR testing at CDC on May 18 confirmed that the patient was infected with the West African
clade of Monkeypox virus. Since then, confirmed cases* have been reported by nine states. …

A comparison of different vitrification devices and the effect of blastocoele collapse on the cryosurvival of in vitro produced porcine embryos

LK Bartolac, JL Lowe, G Koustas… - … of reproduction and …, 2015 - jstage.jst.go.jp
The aim of this study was to determine the optimum conditions for vitrifying in vitro produced
day 7 porcine embryos using different vitrification devices and blastocoele collapse methods…

Effect of different penetrating and non‐penetrating cryoprotectants and media temperature on the cryosurvival of vitrified in vitro produced porcine blastocysts

LK Bartolac, JL Lowe, G Koustas… - Animal Science …, 2018 - Wiley Online Library
The aim of this study was to determine the most efficient vitrification protocol for the cryopreservation
of day 7 in vitro produced ( IVP ) porcine blastocysts. The post‐warm survival rate of …

Detectable clonal mosaicism from birth to old age and its relationship to cancer

…, M De Andrade, SM Armasu, C Regnier, WL Lowe… - Nature …, 2012 - nature.com
We detected clonal mosaicism for large chromosomal anomalies (duplications, deletions
and uniparental disomy) using SNP microarray data from over 50,000 subjects recruited for …