[HTML][HTML] Association between endometriosis and risk of histological subtypes of ovarian cancer: a pooled analysis of case–control studies

…, AM Near, PM Webb, CM Nagle, JA Doherty… - The lancet …, 2012 - thelancet.com
Background Endometriosis is a risk factor for epithelial ovarian cancer; however, whether
this risk extends to all invasive histological subtypes or borderline tumours is not clear. We …

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

…, A González-Neira, MA Rossing, G Pita, JA Doherty… - Nature …, 2013 - nature.com
TERT-locus SNPs and leukocyte telomere measures are reportedly associated with risks of
multiple cancers. Using the Illumina custom genotyping array iCOGs, we analyzed ∼480 …

Invasive epithelial ovarian cancer survival by histotype and disease stage

…, MA Rossing, JM Schildkraut, JA Doherty - JNCI: Journal of the …, 2019 - academic.oup.com
Background The understanding of ovarian cancer pathogenesis has recently shifted to
recognize distinct changes in how ovarian cancer histotypes are defined. Using the 2014 World …

Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

…, K Overvad, A Trichopoulou, R Tumino, JA Doherty… - Nature …, 2017 - nature.com
Although several lung cancer susceptibility loci have been identified, much of the heritability
for lung cancer remains unexplained. Here 14,803 cases and 12,262 controls of European …

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

…, A Dansonka-Mieszkowska, E Despierre, JA Doherty… - Nature …, 2013 - nature.com
Genome-wide association studies (GWAS) have identified four susceptibility loci for
epithelial ovarian cancer (EOC), with another two suggestive loci reaching near genome-wide …

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

…, C Delnatte, KF Doheny, O Diez, YC Ding, JA Doherty… - Nature …, 2017 - nature.com
To identify common alleles associated with different histotypes of epithelial ovarian cancer (EOC),
we pooled data from multiple genome-wide genotyping projects totaling 25,509 EOC …

A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22. 2

…, Z Chen, JM Cunningham, E Dicks, JA Doherty… - Nature …, 2009 - nature.com
Epithelial ovarian cancer has a major heritable component, but the known susceptibility
genes explain less than half the excess familial risk 1 . We performed a genome-wide …

Determinants of telomere length across human tissues

…, F Aguet, H Ahsan, GTEx Consortium*, JA Doherty… - Science, 2020 - science.org
INTRODUCTION Telomeres are DNA-protein complexes located at the end of chromosomes
that protect chromosome ends from degradation and fusion. The DNA component of …

[HTML][HTML] Obesity and risk of ovarian cancer subtypes: evidence from the Ovarian Cancer Association Consortium

…, AH Wu, HA Risch, H Yu, JA Doherty… - Endocrine-related …, 2013 - erc.bioscientifica.com
Whilst previous studies have reported that higher BMI increases a woman's risk of developing
ovarian cancer, associations for the different histological subtypes have not been well …

[PDF][PDF] A quantitative proteome map of the human body

…, NS Abell, J Akey, L Chen, K Demanelis, JA Doherty - Cell, 2020 - cell.com
Determining protein levels in each tissue and how they compare with RNA levels is important
for understanding human biology and disease as well as regulatory processes that control …