[HTML][HTML] Association between endometriosis and risk of histological subtypes of ovarian cancer: a pooled analysis of case–control studies
…, AM Near, PM Webb, CM Nagle, JA Doherty… - The lancet …, 2012 - thelancet.com
Background Endometriosis is a risk factor for epithelial ovarian cancer; however, whether
this risk extends to all invasive histological subtypes or borderline tumours is not clear. We …
this risk extends to all invasive histological subtypes or borderline tumours is not clear. We …
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
…, A González-Neira, MA Rossing, G Pita, JA Doherty… - Nature …, 2013 - nature.com
TERT-locus SNPs and leukocyte telomere measures are reportedly associated with risks of
multiple cancers. Using the Illumina custom genotyping array iCOGs, we analyzed ∼480 …
multiple cancers. Using the Illumina custom genotyping array iCOGs, we analyzed ∼480 …
Invasive epithelial ovarian cancer survival by histotype and disease stage
…, MA Rossing, JM Schildkraut, JA Doherty - JNCI: Journal of the …, 2019 - academic.oup.com
Background The understanding of ovarian cancer pathogenesis has recently shifted to
recognize distinct changes in how ovarian cancer histotypes are defined. Using the 2014 World …
recognize distinct changes in how ovarian cancer histotypes are defined. Using the 2014 World …
Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes
…, K Overvad, A Trichopoulou, R Tumino, JA Doherty… - Nature …, 2017 - nature.com
Although several lung cancer susceptibility loci have been identified, much of the heritability
for lung cancer remains unexplained. Here 14,803 cases and 12,262 controls of European …
for lung cancer remains unexplained. Here 14,803 cases and 12,262 controls of European …
GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer
…, A Dansonka-Mieszkowska, E Despierre, JA Doherty… - Nature …, 2013 - nature.com
Genome-wide association studies (GWAS) have identified four susceptibility loci for
epithelial ovarian cancer (EOC), with another two suggestive loci reaching near genome-wide …
epithelial ovarian cancer (EOC), with another two suggestive loci reaching near genome-wide …
Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer
…, C Delnatte, KF Doheny, O Diez, YC Ding, JA Doherty… - Nature …, 2017 - nature.com
To identify common alleles associated with different histotypes of epithelial ovarian cancer (EOC),
we pooled data from multiple genome-wide genotyping projects totaling 25,509 EOC …
we pooled data from multiple genome-wide genotyping projects totaling 25,509 EOC …
A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22. 2
…, Z Chen, JM Cunningham, E Dicks, JA Doherty… - Nature …, 2009 - nature.com
Epithelial ovarian cancer has a major heritable component, but the known susceptibility
genes explain less than half the excess familial risk 1 . We performed a genome-wide …
genes explain less than half the excess familial risk 1 . We performed a genome-wide …
Determinants of telomere length across human tissues
…, F Aguet, H Ahsan, GTEx Consortium*, JA Doherty… - Science, 2020 - science.org
INTRODUCTION Telomeres are DNA-protein complexes located at the end of chromosomes
that protect chromosome ends from degradation and fusion. The DNA component of …
that protect chromosome ends from degradation and fusion. The DNA component of …
[HTML][HTML] Obesity and risk of ovarian cancer subtypes: evidence from the Ovarian Cancer Association Consortium
Whilst previous studies have reported that higher BMI increases a woman's risk of developing
ovarian cancer, associations for the different histological subtypes have not been well …
ovarian cancer, associations for the different histological subtypes have not been well …
[PDF][PDF] A quantitative proteome map of the human body
Determining protein levels in each tissue and how they compare with RNA levels is important
for understanding human biology and disease as well as regulatory processes that control …
for understanding human biology and disease as well as regulatory processes that control …