User profiles for Jennifer A. Schisa

Jennifer A. Schisa

Professor at Central Michigan University
Verified email at cmich.edu
Cited by 1367

Nanos and pumilio establish embryonic polarity in Drosophila by promoting posterior deadenylation of hunchback mRNA

C Wreden, AC Verrotti, JA Schisa… - …, 1997 - journals.biologists.com
Nanos protein promotes abdominal structures in Drosophila embryos by repressing the
translation of maternal hunchback mRNA in the posterior. To study the mechanism of nanos-…

P granules in the germ cells of Caenorhabditis elegans adults are associated with clusters of nuclear pores and contain RNA

JN Pitt, JA Schisa, JR Priess - Developmental biology, 2000 - Elsevier
The germ cells, and germ cell precursors, in the nematode Caenorhabditis elegans contain
distinctive granules called P granules. During early embryogenesis, P granules are …

[HTML][HTML] Large P body-like RNPs form in C. elegans oocytes in response to arrested ovulation, heat shock, osmotic stress, and anoxia and are regulated by the major …

…, JM Mason, BA Little, PA Padilla, JA Schisa - Developmental …, 2008 - Elsevier
As Caenorhabditis elegans hermaphrodites age, sperm become depleted, ovulation arrests,
and oocytes accumulate in the gonad arm. Large ribonucleoprotein (RNP) foci form in these …

New insights into the regulation of RNP granule assembly in oocytes

JA Schisa - International review of cell and molecular biology, 2012 - Elsevier
In a variety of cell types in plants, animals, and fungi, ribonucleoprotein (RNP) complexes
play critical roles in regulating RNA metabolism. These RNP granules include processing …

Analysis of RNA associated with P granules in germ cells of C. elegans adults

J A. Schisa, J N. Pitt, J R. Priess - Development, 2001 - journals.biologists.com
P granules are cytoplasmic structures of unknown function that are associated with germ
nuclei in the C. elegans gonad, and are localized exclusively to germ cells, or germ cell …

[HTML][HTML] C. elegans Dicer interacts with the P-granule component GLH-1 and both regulate germline RNPs

…, TJ McEwen, MC Jud, JK Marshall, JA Schisa… - Developmental …, 2011 - Elsevier
P granules, ribonucleoprotein (RNP) complexes specific to the cytoplasmic side of the nuclear
pores of Caenorhabditis elegans germ cells, are implicated in post-transcriptional control …

[HTML][HTML] An emerging role for post-translational modifications in regulating RNP condensates in the germ line

JA Schisa, MT Elaswad - Frontiers in molecular biosciences, 2021 - frontiersin.org
RNA-binding proteins undergo regulated phase transitions in an array of cell types. The
phase separation of RNA-binding proteins, and subsequent formation of RNP condensates or …

[HTML][HTML] Assembly of RNP granules in stressed and aging oocytes requires nucleoporins and is coordinated with nuclear membrane blebbing

JR Patterson, MP Wood, JA Schisa - Developmental biology, 2011 - Elsevier
Protective cellular responses to stress and aging in the germline are essential for perpetuation
of a species; however, relatively few studies have focused on how germ cells respond to …

ifet-1 is a broad-scale translational repressor required for normal P granule formation in C. elegans

…, TH Beilharz, MP Colaiácovo, JA Schisa… - Journal of cell …, 2013 - journals.biologists.com
Large cytoplasmic ribonucleoprotein germ granule complexes are a common feature in
germ cells. In C. elegans these are called P granules and for much of the life-cycle they …

Conservation of large foci formation in arrested oocytes of Caenorhabditis nematodes

…, J Razelun, J Bickel, M Czerwinski, JA Schisa - Development genes and …, 2007 - Springer
Within the rhabditid phylogeny of nematodes, the great majority of species are gonochoristic,
having evolved as obligate male/female species. In contrast, the well-studied nematode …