User profiles for Jennifer C. Waters
Jennifer C WatersHarvard Medical School Verified email at hms.harvard.edu Cited by 4709 |
Accuracy and precision in quantitative fluorescence microscopy
JC Waters - 2009 - rupress.org
The light microscope has long been used to document the localization of fluorescent
molecules in cell biology research. With advances in digital cameras and the discovery and …
molecules in cell biology research. With advances in digital cameras and the discovery and …
Localization of Mad2 to kinetochores depends on microtubule attachment, not tension
… We then fixed the cells and measured the distance between sister kinetochores in metaphase
cells (36 chromosomes in 6 cells) as described above and in Waters et al. (1996a). We …
cells (36 chromosomes in 6 cells) as described above and in Waters et al. (1996a). We …
Association of spindle assembly checkpoint component XMAD2 with unattached kinetochores
The spindle assembly checkpoint delays anaphase until all chromosomes are attached to a
mitotic spindle. The mad (mitotic arrest-deficient) and bub (budding uninhibited by …
mitotic spindle. The mad (mitotic arrest-deficient) and bub (budding uninhibited by …
Phototoxicity in live fluorescence microscopy, and how to avoid it
Phototoxicity frequently occurs during live fluorescence microscopy, and its consequences
are often underestimated. Damage to cellular macromolecules upon excitation light …
are often underestimated. Damage to cellular macromolecules upon excitation light …
[HTML][HTML] Vertebrate shugoshin links sister centromere cohesion and kinetochore microtubule stability in mitosis
A Salic, JC Waters, TJ Mitchison - Cell, 2004 - cell.com
Drosophila MEI-S332 and fungal Sgo1 genes are essential for sister centromere cohesion
in meiosis I. We demonstrate that the related vertebrate Sgo localizes to kinetochores and is …
in meiosis I. We demonstrate that the related vertebrate Sgo localizes to kinetochores and is …
Rapid image deconvolution and multiview fusion for optical microscopy
The contrast and resolution of images obtained with optical microscopes can be improved
by deconvolution and computational fusion of multiple views of the same sample, but these …
by deconvolution and computational fusion of multiple views of the same sample, but these …
Oscillating mitotic newt lung cell kinetochores are, on average, under tension and rarely push
JC Waters, RV Skibbens… - Journal of cell …, 1996 - journals.biologists.com
Experimentally introduced tension on kinetochores and their centromeres has been shown
to stabilize kinetochore attachment to microtubules, modify kinetochore directional instability, …
to stabilize kinetochore attachment to microtubules, modify kinetochore directional instability, …
Evaluating performance in three‐dimensional fluorescence microscopy
…, PL Appleton, JR Swedlow, JC Waters - Journal of …, 2007 - Wiley Online Library
In biological fluorescence microscopy, image contrast is often degraded by a high
background arising from out of focus regions of the specimen. This background can be greatly …
background arising from out of focus regions of the specimen. This background can be greatly …
Designing a rigorous microscopy experiment: Validating methods and avoiding bias
APT Jost, JC Waters - Journal of Cell Biology, 2019 - rupress.org
Images generated by a microscope are never a perfect representation of the biological
specimen. Microscopes and specimen preparation methods are prone to error and can impart …
specimen. Microscopes and specimen preparation methods are prone to error and can impart …
[HTML][HTML] Direction of actin flow dictates integrin LFA-1 orientation during leukocyte migration
Integrin αβ heterodimer cell surface receptors mediate adhesive interactions that provide
traction for cell migration. Here, we test whether the integrin, when engaged to an extracellular …
traction for cell migration. Here, we test whether the integrin, when engaged to an extracellular …