There is significant clinical demand for functional tendon grafts in human and veterinary
medicine. Tissue engineering techniques combining cells, scaffolds, and environmental stimuli …

Natural extracellular matrix provides a number of distinct advantages for engineering replacement
orthopedic tissue due to its intrinsic functional properties. The goal of this study was to …

The mechanisms by which kinesin-related proteins interact with other proteins to carry out
specific cellular processes is poorly understood. The kinesin-related protein, Kar3p, has been …

Tendons are frequently damaged and fail to regenerate, leading to pain, loss of function,
and reduced quality of life. Mesenchymal stem cells (MSCs) possess clinically useful tissue-…

Objective To report clinical findings and outcomes for 55 dogs with supraspinatus
tendinopathy (ST) treated with adipose-derived progenitor cells and platelet-rich plasma (ADPC-PRP) …

Bioreactors are powerful tools with the potential to model tissue development and disease
in vitro. For nearly four decades, bioreactors have been used to create tendon and ligament …

Tendons bridge muscle and bone, translating forces to the skeleton and increasing the
safety and efficiency of locomotion. When tendons fail or degenerate, there are no effective …

One hallmark of mesenchymal stem cells (MSCs) is the ability to differentiate into multiple
tissue types which assists in tissue regeneration. Another hallmark of MSCs is their potent anti-…

Adult tissue stem cells have shown promise for the treatment of debilitating tendon injuries.
However, few comparisons of stem cells from different tissue sources have been made to …

Three-dimensional (3D) culture of human mesenchymal stem cells (MSCs) as spheroids
enhances the production of important regulators of inflammation: prostaglandin E2 (PGE 2 ), …