The spatial architecture of the islets of Langerhans is hypothesized to facilitate synchronized
insulin secretion among β cells, yet testing this in vivo in the intact pancreas is challenging. …

The islets of Langerhans exist as multicellular networks that regulate blood glucose levels.
The majority of cells in the islet are excitable, insulin-producing β-cells that are electrically …

Diabetes is caused by the inability of electrically coupled, functionally heterogeneous β-cells
within the pancreatic islet to provide adequate insulin secretion. Functional networks have …

Neurocritical care patients may benefit from personalized treatment based on their cerebral
autoregulatory function. The pressure reactivity index is an important, prevalent metric used …

Network theory provides tools for quantifying communication within heterogeneous
biological systems. Calcium-based imaging is a common technique used to analyze cellular …

Understanding how insulin secretion is regulated and how the b-cells and islets become
dysfunctional is critical to understanding and treating diabetes. The islets of Langerhans are …

Sunday, February 20, 2022 125a activity is coordinated by gap junction channels. b-cell Ca2þ
activity is globally elevated at high glucose, whereas it is globally silenced at low glucose …

This paper presents observations of dayside auroral signatures resulting from a massive
localized compression of the magnetopause, magnetosheath, and bow shock. On 10 …

The pancreatic Islet is composed of hundreds of highly heterogeneous, insulin-secreting beta
cells. Gap-junction protein channels form links between this complex network of dynamic …

The Sloan Digital Sky Survey (SDSS) is an imaging and spectroscopic survey that will
eventually cover approximately one-quarter of the celestial sphere and collect spectra of≈ 10 6 …