[HTML][HTML] Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis

…, A Muruato, J Zou, X Zhang, T Juelich, JK Smith… - Nature, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)—a new coronavirus that
has led to a worldwide pandemic 1 —has a furin cleavage site (PRRAR) in its spike protein …

[HTML][HTML] Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol

…, R Aliyari, K Chikere, G Li, MD Marsden, JK Smith… - Immunity, 2013 - Elsevier
Interferons (IFN) are essential antiviral cytokines that establish the cellular antiviral state
through upregulation of hundreds of interferon-stimulated genes (ISGs), most of which have …

Hate crime: An emergent research agenda

DP Green, LH McFalls, JK Smith - Annual review of sociology, 2001 - annualreviews.org
Hate crime is difficult to define, measure, and explain. After summarizing some of the
leading conceptual issues and theoretical perspectives, we discuss the practical difficulties …

[HTML][HTML] Furin cleavage site is key to SARS-CoV-2 pathogenesis

…, A Muruato, J Zou, X Zhang, T Juelich, JK Smith… - BioRxiv, 2020 - ncbi.nlm.nih.gov
SARS-CoV-2 has resulted in a global pandemic and shutdown economies around the world.
Sequence analysis indicates that the novel coronavirus (CoV) has an insertion of a furin …

Unwritten rules: Informal institutions in established democracies

JR Azari, JK Smith - Perspectives on Politics, 2012 - cambridge.org
Scholars of the developing world have driven a surge of interest in unwritten or informal
institutions as determinants of political outcomes. In advanced industrial democracies, by …

The effects of 37 hours of continuous wakefulness on the physiological arousal, cognitive performance, self-reported mood, and simulator flight performance of F-117A …

…, JL Caldwell, DL Brown, JK Smith - Military Psychology, 2004 - Taylor & Francis
Pilot fatigue poses a serious threat to operational safety, but understanding the nature of the
problem and the times at which pilots are most at risk will facilitate operationally relevant …

[HTML][HTML] Favipiravir (T-705) protects against Nipah virus infection in the hamster model

…, B Kalveram, T Ikegami, T Juelich, JK Smith… - Scientific reports, 2018 - nature.com
Nipah and Hendra viruses are recently emerged bat-borne paramyxoviruses (genus
Henipavirus) causing severe encephalitis and respiratory disease in humans with fatality rates …

[HTML][HTML] A mechanistic paradigm for broad-spectrum antivirals that target virus-cell fusion

…, S Chou, MARB Castanho, MC Wolf, JK Smith… - PLoS …, 2013 - journals.plos.org
LJ001 is a lipophilic thiazolidine derivative that inhibits the entry of numerous enveloped
viruses at non-cytotoxic concentrations (IC 50 ≤0.5 µM), and was posited to exploit the …

Modafinil's effects on simulator performance and mood in pilots during 37 h without sleep

JA Caldwell, JL Caldwell, JK Smith… - Aviation, space, and …, 2004 - ingentaconnect.com
Caldwell JA, Caldwell JL, Brown DL, Smith JK. Modafinil’s effects on simulator performance
and mood in pilots during 37 h without sleep. Aviat Space Environ Med 2004; 75:777–784. …

[HTML][HTML] Favipiravir (T-705) inhibits Junin virus infection and reduces mortality in a guinea pig model of Argentine hemorrhagic fever

…, TL Juelich, EJ Sefing, T Brasel, JK Smith… - PLoS neglected …, 2013 - journals.plos.org
Background Junín virus (JUNV), the etiologic agent of Argentine hemorrhagic fever (AHF),
is classified by the NIAID and CDC as a Category A priority pathogen. Presently, antiviral …