User profiles for Jennifer L. Gardy
Jennifer GardyBill & Melinda Gates Foundation Verified email at gatesfoundation.org Cited by 11321 |
[HTML][HTML] Whole-genome sequencing and social-network analysis of a tuberculosis outbreak
Background An outbreak of tuberculosis occurred over a 3-year period in a medium-size
community in British Columbia, Canada. The results of mycobacterial interspersed repetitive unit…
community in British Columbia, Canada. The results of mycobacterial interspersed repetitive unit…
PSORTb v. 2.0: expanded prediction of bacterial protein subcellular localization and insights gained from comparative proteome analysis
Motivation: PSORTb v.1.1 is the most precise bacterial localization prediction tool available.
However, the program's predictive coverage and recall are low and the method is only …
However, the program's predictive coverage and recall are low and the method is only …
[HTML][HTML] Towards a genomics-informed, real-time, global pathogen surveillance system
The recent Ebola and Zika epidemics demonstrate the need for the continuous surveillance,
rapid diagnosis and real-time tracking of emerging infectious diseases. Fast, affordable …
rapid diagnosis and real-time tracking of emerging infectious diseases. Fast, affordable …
PSORT-B: Improving protein subcellular localization prediction for Gram-negative bacteria
Automated prediction of bacterial protein subcellular localization is an important tool for
genome annotation and drug discovery. PSORT has been one of the most widely used …
genome annotation and drug discovery. PSORT has been one of the most widely used …
Genomic analysis identifies targets of convergent positive selection in drug-resistant Mycobacterium tuberculosis
M. tuberculosis is evolving antibiotic resistance, threatening attempts at tuberculosis epidemic
control. Mechanisms of resistance, including genetic changes favored by selection in …
control. Mechanisms of resistance, including genetic changes favored by selection in …
InnateDB: facilitating systems‐level analyses of the mammalian innate immune response
Although considerable progress has been made in dissecting the signaling pathways involved
in the innate immune response, it is now apparent that this response can no longer be …
in the innate immune response, it is now apparent that this response can no longer be …
[HTML][HTML] Association between the 2008–09 seasonal influenza vaccine and pandemic H1N1 illness during spring–summer 2009: four observational studies from …
Background In late spring 2009, concern was raised in Canada that prior vaccination with the
2008–09 trivalent inactivated influenza vaccine (TIV) was associated with increased risk of …
2008–09 trivalent inactivated influenza vaccine (TIV) was associated with increased risk of …
The Commensal Streptococcus salivarius K12 Downregulates the Innate Immune Responses of Human Epithelial Cells and Promotes Host-Microbe Homeostasis
…, DA Devine, E Dullaghan, JL Gardy… - Infection and …, 2008 - Am Soc Microbiol
Streptococcus salivarius is an early colonizer of human oral and nasopharyngeal epithelia,
and strain K12 has reported probiotic effects. An emerging paradigm indicates that …
and strain K12 has reported probiotic effects. An emerging paradigm indicates that …
[HTML][HTML] Metagenomics for pathogen detection in public health
Traditional pathogen detection methods in public health infectious disease surveillance rely
upon the identification of agents that are already known to be associated with a particular …
upon the identification of agents that are already known to be associated with a particular …
Methods for predicting bacterial protein subcellular localization
JL Gardy, FSL Brinkman - Nature Reviews Microbiology, 2006 - nature.com
The computational prediction of the subcellular localization of bacterial proteins is an important
step in genome annotation and in the search for novel vaccine or drug targets. Since the …
step in genome annotation and in the search for novel vaccine or drug targets. Since the …