Interaction of polycyclic musks and UV filters with the estrogen receptor (ER), androgen receptor (AR), and progesterone receptor (PR) in reporter gene bioassays
RHMM Schreurs, E Sonneveld, JHJ Jansen… - Toxicological …, 2005 - academic.oup.com
Two important ingredients of personal care products, namely polycyclic musk fragrances
and UV filters, can be found in the environment and in humans. In previous studies, several …
and UV filters, can be found in the environment and in humans. In previous studies, several …
[HTML][HTML] The role of the small intestine in the development of dietary fat-induced obesity and insulin resistance in C57BL/6J mice
…, GJEJ Hooiveld, MMG Bromhaar, J Jansen… - BMC medical …, 2008 - Springer
Background Obesity and insulin resistance are two major risk factors underlying the metabolic
syndrome. The development of these metabolic disorders is frequently studied, but mainly …
syndrome. The development of these metabolic disorders is frequently studied, but mainly …
[HTML][HTML] Humoral immune escape by current SARS-CoV-2 variants BA. 2.86 and JN. 1, December 2023
…, F Walper, ML Schmidt, J Jansen… - …, 2024 - eurosurveillance.org
Variant BA.2.86 and its descendant, JN.1, of SARS-CoV-2 are rising in incidence across
Europe and globally. We isolated recent JN.1, BA.2.86, EG.5, XBB.1.5 and earlier variants. We …
Europe and globally. We isolated recent JN.1, BA.2.86, EG.5, XBB.1.5 and earlier variants. We …
[HTML][HTML] Postprandial dietary lipid–specific effects on human peripheral blood mononuclear cell gene expression profiles
M Bouwens, MG Bromhaar, J Jansen, M Müller… - The American journal of …, 2010 - Elsevier
Background: Dietary polyunsaturated fatty acids (PUFAs) have a variety of beneficial effects,
and immune cells play an important role in these effects. The mechanisms of action of …
and immune cells play an important role in these effects. The mechanisms of action of …
[HTML][HTML] Expression profiling of pectinolytic genes from Aspergillus niger
RP de Vries, J Jansen, G Aguilar, L Pařenicová… - FEBS letters, 2002 - Elsevier
The expression of 26 pectinolytic genes from Aspergillus niger was studied in a wild type
strain and a CreA derepressed strain, under 16 different growth conditions, to obtain an …
strain and a CreA derepressed strain, under 16 different growth conditions, to obtain an …
[HTML][HTML] SARS-CoV-2 variant Alpha has a spike-dependent replication advantage over the ancestral B. 1 strain in human cells with low ACE2 expression
…, J Trimpert, J Heinze, A Richter, J Jansen… - PLoS …, 2022 - journals.plos.org
Epidemiological data demonstrate that Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
variants of concern (VOCs) Alpha and Delta are more transmissible, infectious…
variants of concern (VOCs) Alpha and Delta are more transmissible, infectious…
[HTML][HTML] Phosphatidylserine-exposing extracellular vesicles in body fluids are an innate defence against apoptotic mimicry viral pathogens
…, M Cortese, D Gupta, M Deniz, JY Choi, J Jansen… - Nature …, 2024 - nature.com
Some viruses are rarely transmitted orally or sexually despite their presence in saliva, breast
milk, or semen. We previously identified that extracellular vesicles (EVs) in semen and …
milk, or semen. We previously identified that extracellular vesicles (EVs) in semen and …
[HTML][HTML] Early and rapid identification of COVID-19 patients with neutralizing type I interferon auto-antibodies
…, O Staudacher, D Niemeyer, J Jansen… - Journal of clinical …, 2022 - Springer
Purpose Six to 19% of critically ill COVID-19 patients display circulating auto-antibodies against
type I interferons (IFN-AABs). Here, we establish a clinically applicable strategy for early …
type I interferons (IFN-AABs). Here, we establish a clinically applicable strategy for early …
Nonproductive exposure of PBMCs to SARS‐CoV‐2 induces cell‐intrinsic innate immune responses
…, J Emanuel, C Fischer, J Jansen… - Molecular Systems …, 2022 - embopress.org
Cell‐intrinsic responses mounted in PBMCs during mild and severe COVID‐19 differ
quantitatively and qualitatively. Whether they are triggered by signals emitted by productively …
quantitatively and qualitatively. Whether they are triggered by signals emitted by productively …
Absence of cGAS-mediated type I IFN responses in HIV-1–infected T cells
…, J Kazmierski, T Zillinger, J Jansen… - Proceedings of the …, 2020 - National Acad Sciences
The DNA sensor cGAS catalyzes the production of the cyclic dinucleotide cGAMP, resulting
in type I interferon responses. We addressed the functionality of cGAS-mediated DNA …
in type I interferon responses. We addressed the functionality of cGAS-mediated DNA …