Simulations of close relatives and identical by descent (IBD) segments are common in
genetic studies, yet most past efforts have utilized sex averaged genetic maps and ignored …

Multiple-objective optimization is common in biological systems. In the mammalian olfactory
system, each sensory neuron stochastically expresses only one out of up to thousands of …

The proportion of samples with one or more close relatives in a genetic dataset increases
rapidly with sample size, necessitating relatedness modeling and enabling pedigree-based …

The proportion of samples with one or more close relatives in a genetic dataset increases
rapidly with sample size, necessitating relatedness modeling and enabling pedigree-based …

Large genomic datasets abound with unreported relatives, making them a prime candidate
for identifying latent pedigree structures. However, the most commonly applied methods for …

Multiple-objective optimization is common in biological systems. In the mammalian olfactory
system, each sensory neuron stochastically expresses only one out of up to thousands of …

The design of active and selective catalysts is essential for a wide range of industrial
applications and societal issues. A fundamental approach is to identify the key elementary steps …

The fraction of relatives in large genetic databases is continuously increasing, making it
more vital to uncover the relationships among samples for further downstream analysis. …

Faithful replication of the DNA is critical for cell proliferation and genome stability. In eukaryotes,
initiation and progression of DNA replication is highly organized in both space and time. …

… We thank Ying Qiao and Jens Sannerud for help in testing, and the anonymous reviewers
for suggested analyses. This work was supported by NIH grant R35 GM133805, an Alfred P. …