The homing endonuclease I‐ Cre I recognizes and cleaves a particular 22 bp DNA sequence.
The crystal structure of I‐ Cre I bound to homing site DNA has previously been determined…

The National Cancer Institute (NCI) Genomic Data Commons (GDC) contains more than 2.9
petabytes of genomic and associated clinical data from more than 60 NCI-funded and other …

The goal of the National Cancer Institute’s (NCI’s) Genomic Data Commons (GDC) is to
provide the cancer research community with a data repository of uniformly processed genomic …

Utilizing the structure–activity relationship we have developed during the synthesis of the
first two generations and mechanism of action studies that point to the interaction of these …

The first critical stage in salamander or teleost appendage regeneration is creation of a
specialized epidermis that instructs growth from underlying stump tissue. Here, we performed a …

We have developed and used a genetic selection system in Escherichia coli to study functional
requirements for homing site recognition and cleavage by a representative eukaryotic …

The neuronal primary cilium and centriolar satellites have functions in neurogenesis, but
little is known about their roles in the postnatal brain. We show that ablation of pericentriolar …

… Rolf Muller, Jeremiah Savage and Ying Lin screened the combinatorial chemical library for
HIV-1 protease inhibitory activity. Ying Lin and Jeremiah Savage produced the protease for …

The expression of PU.1, a member of the ets transcription factor family, is limited to the
hematopoietic lineage. Using knockout and reduced PU.1 expression and gain of function mice …

… In the book of Jeremiah, the nation has lost shalom /health because of its sin-idolatry. … This
study proposes that the fracturing of shalom /health in the Psalms and Jeremiah is primarily of …