UCSF protocol for caries arrest using silver diamine fluoride: rationale, indications and consent

JA Horst, H Ellenikiotis, PL Milgrom - Journal of the California …, 2016 - Taylor & Francis
The Food and Drug Administration recently cleared silver diamine fluoride for reducing tooth
sensitivity. Clinical trials document arrest and prevention of dental caries by silver diamine …

Fluorides and other preventive strategies for tooth decay

JA Horst, JM Tanzer, PM Milgrom - Dental Clinics, 2018 - dental.theclinics.com
This article focuses on strategies to reduce the burden of dental caries across the population,
using fluorides and some other dental caries preventive agents. It is imperative to be …

[HTML][HTML] Caries induced cytokine network in the odontoblast layer of human teeth

OV Horst, JA Horst, R Samudrala, BA Dale - BMC immunology, 2011 - Springer
Background Immunologic responses of the tooth to caries begin with odontoblasts recognizing
carious bacteria. Inflammatory propagation eventually leads to tooth pulp necrosis and …

Novel paradigms for drug discovery: computational multitarget screening

E Jenwitheesuk, JA Horst, KL Rivas… - Trends in …, 2008 - cell.com
An established paradigm in current drug development is (i) to identify a single protein target
whose inhibition is likely to result in the successful treatment of a disease of interest; (ii) to …

[HTML][HTML] Topical silver diamine fluoride for dental caries arrest in preschool children: A randomized controlled trial and microbiological analysis of caries associated …

P Milgrom, JA Horst, S Ludwig, M Rothen, BW Chaffee… - Journal of dentistry, 2018 - Elsevier
Objectives The Stopping Cavities Trial investigated effectiveness and safety of 38% silver
diamine fluoride in arresting caries lesions. Materials and methods The study was a double-…

[HTML][HTML] Amyloid-like ribbons of amelogenins in enamel mineralization

KMM Carneiro, H Zhai, L Zhu, JA Horst, M Sitlin… - Scientific reports, 2016 - nature.com
Enamel, the outermost layer of teeth, is an acellular mineralized tissue that cannot regenerate;
the mature tissue is composed of high aspect ratio apatite nanocrystals organized into …

Methicillin-resistant Staphylococcus aureus from dental school clinic surfaces and students

MC Roberts, OO Soge, JA Horst, KA Ly… - American journal of …, 2011 - Elsevier
BACKGROUND: Methicillin-resistant Staphylococcus aureus (MRSA) isolated from frequently
touched dental school clinic surfaces were compared with MRSA isolated nasal cultures of …

[PDF][PDF] A human homeotic transformation resulting from mutations in PLCB4 and GNAI3 causes auriculocondylar syndrome

…, DA Nickerson, TC Cox, AV Hing, JA Horst… - The American Journal of …, 2012 - cell.com
Auriculocondylar syndrome (ACS) is a rare, autosomal-dominant craniofacial malformation
syndrome characterized by variable micrognathia, temporomandibular joint ankylosis, cleft …

[HTML][HTML] Managing dental caries against the backdrop of COVID-19: approaches to reduce aerosol generation

E Eden, J Frencken, S Gao, JA Horst, N Innes - British dental journal, 2020 - nature.com
The COVID-19 pandemic resulted in severe limitation and closure of dental practices in
many countries. Outside of the acute (peak) phases of the disease, dentistry has begun to be …

[HTML][HTML] Cementomimetics—constructing a cementum-like biomineralized microlayer via amelogenin-derived peptides

M Gungormus, EE Oren, JA Horst, H Fong… - International journal of …, 2012 - nature.com
Cementum is the outer-, mineralized-tissue covering the tooth root and an essential part of
the system of periodontal tissue that anchors the tooth to the bone. Periodontal disease …