Histopathology is insufficient to predict disease progression and clinical outcome in lung
adenocarcinoma. Here we show that gene-expression profiles based on microarray analysis …

The t distribution provides a useful extension of the normal for statistical modeling of data
sets involving errors with longer-than-normal tails. An analytical strategy based on maximum …

We evaluated three cellular and five serologic markers that are affected by infection with the
human immunodeficiency virus type 1 (HIV-1 ) for their ability to predict the progression to …

The relationship between gene expression measured at the mRNA level and the corresponding
protein level is not well characterized in human cancer. In this study, we compared …

The success of genome-wide association (GWA) studies for the detection of sequence
variation affecting complex traits in human has spurred interest in the use of large-scale high-…

The imprints of domestication and breed development on the genomes of livestock likely differ
from those of companion animals. A deep draft sequence assembly of shotgun reads from …

Background: A surrogate marker for treatment response that can be observed earlier than
comparison of sequential magnetic resonance imaging (MRI) scans, which depends on …

High-density single-nucleotide polymorphism (SNP) arrays have revolutionized the ability of
genome-wide association studies to detect genomic regions harboring sequence variants …

Some failure time data come from a population that consists of some subjects who are
susceptible to and others who are nonsusceptible to the event of interest. The data typically have …

Background The dissection of complex traits of economic importance to the pig industry
requires the availability of a significant number of genetic markers, such as single nucleotide …