Conserved cell types with divergent features in human versus mouse cortex
Elucidating the cellular architecture of the human cerebral cortex is central to understanding
our cognitive abilities and susceptibility to disease. Here we used single-nucleus RNA-…
our cognitive abilities and susceptibility to disease. Here we used single-nucleus RNA-…
[HTML][HTML] Comparative cellular analysis of motor cortex in human, marmoset and mouse
The primary motor cortex (M1) is essential for voluntary fine-motor control and is functionally
conserved across mammals 1 . Here, using high-throughput transcriptomic and epigenomic …
conserved across mammals 1 . Here, using high-throughput transcriptomic and epigenomic …
Genetic programming for data classification: Partitioning the search space
J Eggermont, JN Kok, WA Kosters - … of the 2004 ACM symposium on …, 2004 - dl.acm.org
When Genetic Programming is used to evolve decision trees for data classification, search
spaces tend to become extremely large. We present several methods using techniques from …
spaces tend to become extremely large. We present several methods using techniques from …
Memory CD4+ T cells are generated in the human fetal intestine
…, T Höllt, OV Britanova, J Eggermont… - Nature …, 2019 - nature.com
The fetus is thought to be protected from exposure to foreign antigens, yet CD45RO + T cells
reside in the fetal intestine. Here we combined functional assays with mass cytometry, single…
reside in the fetal intestine. Here we combined functional assays with mass cytometry, single…
Comparative transcriptomics reveals human-specific cortical features
The cognitive abilities of humans are distinctive among primates, but their molecular and
cellular substrates are poorly understood. We used comparative single-nucleus transcriptomics …
cellular substrates are poorly understood. We used comparative single-nucleus transcriptomics …
Mixed integer evolution strategies for parameter optimization
R Li, MTM Emmerich, J Eggermont… - Evolutionary …, 2013 - ieeexplore.ieee.org
Evolution strategies (ESs) are powerful probabilistic search and optimization algorithms
gleaned from biological evolution theory. They have been successfully applied to a wide range …
gleaned from biological evolution theory. They have been successfully applied to a wide range …
Evolution of cellular diversity in primary motor cortex of human, marmoset monkey, and mouse
The primary motor cortex (M1) is essential for voluntary fine motor control and is functionally
conserved across mammals. Using high-throughput transcriptomic and epigenomic profiling …
conserved across mammals. Using high-throughput transcriptomic and epigenomic profiling …
Tissue characterization with depth-resolved attenuation coefficient and backscatter term in intravascular optical coherence tomography images
S Liu, Y Sotomi, J Eggermont… - … of biomedical optics, 2017 - spiedigitallibrary.org
An important application of intravascular optical coherence tomography (IVOCT) for
atherosclerotic tissue analysis is using it to estimate attenuation and backscatter coefficients. This …
atherosclerotic tissue analysis is using it to estimate attenuation and backscatter coefficients. This …
[HTML][HTML] Automatic stent strut detection in intravascular optical coherence tomographic pullback runs
A Wang, J Eggermont, N Dekker… - The international journal …, 2013 - Springer
We developed and evaluated an automatic stent strut detection method in intravascular
optical coherence tomography (IVOCT) pullback runs. Providing very high resolution images, …
optical coherence tomography (IVOCT) pullback runs. Providing very high resolution images, …
[HTML][HTML] Immune subset-committed proliferating cells populate the human foetal intestine throughout the second trimester of gestation
…, AA Vloemans, J Eggermont… - Nature …, 2023 - nature.com
The intestine represents the largest immune compartment in the human body, yet its development
and organisation during human foetal development is largely unknown. Here we show …
and organisation during human foetal development is largely unknown. Here we show …