Conserved cell types with divergent features in human versus mouse cortex

…, B Long, N Johansen, O Penn, Z Yao, J Eggermont… - Nature, 2019 - nature.com
Elucidating the cellular architecture of the human cerebral cortex is central to understanding
our cognitive abilities and susceptibility to disease. Here we used single-nucleus RNA-…

[HTML][HTML] Comparative cellular analysis of motor cortex in human, marmoset and mouse

…, RD Hodge, FM Krienen, SA Sorensen, J Eggermont… - Nature, 2021 - nature.com
The primary motor cortex (M1) is essential for voluntary fine-motor control and is functionally
conserved across mammals 1 . Here, using high-throughput transcriptomic and epigenomic …

Genetic programming for data classification: Partitioning the search space

J Eggermont, JN Kok, WA Kosters - … of the 2004 ACM symposium on …, 2004 - dl.acm.org
When Genetic Programming is used to evolve decision trees for data classification, search
spaces tend to become extremely large. We present several methods using techniques from …

Memory CD4+ T cells are generated in the human fetal intestine

…, T Höllt, OV Britanova, J Eggermont… - Nature …, 2019 - nature.com
The fetus is thought to be protected from exposure to foreign antigens, yet CD45RO + T cells
reside in the fetal intestine. Here we combined functional assays with mass cytometry, single…

Comparative transcriptomics reveals human-specific cortical features

…, D Bertagnolli, M Crow, SL Ding, J Eggermont… - Science, 2023 - science.org
The cognitive abilities of humans are distinctive among primates, but their molecular and
cellular substrates are poorly understood. We used comparative single-nucleus transcriptomics …

Mixed integer evolution strategies for parameter optimization

R Li, MTM Emmerich, J Eggermont… - Evolutionary …, 2013 - ieeexplore.ieee.org
Evolution strategies (ESs) are powerful probabilistic search and optimization algorithms
gleaned from biological evolution theory. They have been successfully applied to a wide range …

Evolution of cellular diversity in primary motor cortex of human, marmoset monkey, and mouse

…, RD Hodge, FM Krienen, SA Sorensen, J Eggermont… - BioRxiv, 2020 - biorxiv.org
The primary motor cortex (M1) is essential for voluntary fine motor control and is functionally
conserved across mammals. Using high-throughput transcriptomic and epigenomic profiling …

Tissue characterization with depth-resolved attenuation coefficient and backscatter term in intravascular optical coherence tomography images

S Liu, Y Sotomi, J Eggermont… - … of biomedical optics, 2017 - spiedigitallibrary.org
An important application of intravascular optical coherence tomography (IVOCT) for
atherosclerotic tissue analysis is using it to estimate attenuation and backscatter coefficients. This …

[HTML][HTML] Automatic stent strut detection in intravascular optical coherence tomographic pullback runs

A Wang, J Eggermont, N Dekker… - The international journal …, 2013 - Springer
We developed and evaluated an automatic stent strut detection method in intravascular
optical coherence tomography (IVOCT) pullback runs. Providing very high resolution images, …

[HTML][HTML] Immune subset-committed proliferating cells populate the human foetal intestine throughout the second trimester of gestation

…, AA Vloemans, J Eggermont… - Nature …, 2023 - nature.com
The intestine represents the largest immune compartment in the human body, yet its development
and organisation during human foetal development is largely unknown. Here we show …