In Drosophila melanogaster, Hox genes are organized in an anterior and a posterior cluster,
called Antennapedia complex and bithorax complex, located on the same chromosome arm …

Organisms must process information encoded via developmental and environmental signals
to survive and reproduce. Researchers have also engineered synthetic genetic logic to …

Cell-free transcription–translation systems have great potential for biosensing, yet the range
of detectable chemicals is limited. Here we provide a workflow to expand the range of …

Whole-cell biosensors have several advantages for the detection of biological substances
and have proven to be useful analytical tools. However, several hurdles have limited whole-…

The use of synthetic biological systems in research, healthcare, and manufacturing often
requires autonomous history-dependent behavior and therefore some form of engineered …

Libraries of well-characterised components regulating gene expression levels are essential
to many synthetic biology applications. While widely available for the Gram-negative model …

Living cells have evolved to detect and process various signals and can self‐replicate,
presenting an attractive platform for engineering scalable and affordable biosensing devices. …

Bacterial biosensors, or bactosensors, are promising agents for medical and environmental
diagnostics. However, the lack of scalable frameworks to systematically program ligand …

Synthetic biological circuits are promising tools for developing sophisticated systems for
medical, industrial, and environmental applications. So far, circuit implementations commonly …

Engineered bacteria promise to revolutionize diagnostics and therapeutics, yet many applications
are precluded by the limited number of detectable signals. Here we present a general …