Poliovirus and poliomyelitis: a tale of guts, brains, and an accidental event

S Mueller, E Wimmer, J Cello - Virus research, 2005 - Elsevier
Nearly 100 years after its discovery poliovirus remains one of most thoroughly studied and
best understood virus models for the molecular virologist. While poliovirus has been of vital …

Chemical synthesis of poliovirus cDNA: generation of infectious virus in the absence of natural template

J Cello, AV Paul, E Wimmer - science, 2002 - science.org
Full-length poliovirus complementary DNA (cDNA) was synthesized by assembling oligonucleotides
of plus and minus strand polarity. The synthetic poliovirus cDNA was transcribed by …

Oncolytic treatment and cure of neuroblastoma by a novel attenuated poliovirus in a novel poliovirus-susceptible animal model

H Toyoda, J Yin, S Mueller, E Wimmer, J Cello - Cancer research, 2007 - AACR
Neuroblastoma is one of the most common solid tumors in children. Treatment is of limited
utility for high-risk neuroblastoma and prognosis is poor. Resistance of neuroblastoma to …

Mutation of a single conserved nucleotide between the cloverleaf and internal ribosome entry site attenuates poliovirus neurovirulence

…, D Franco, A Paul, E Wimmer, J Cello - Journal of virology, 2005 - Am Soc Microbiol
The chemical synthesis of poliovirus (PV) cDNA combined with the cell-free synthesis of
infectious particles yielded virus whose mouse neurovirulence was highly attenuated (J. Cello, …

[HTML][HTML] Dry heat sterilization as a method to recycle N95 respirator masks: The importance of fit

JG Yuen, AC Marshilok, PT Benziger, S Yan, J Cello… - PLoS …, 2022 - journals.plos.org
In times of crisis, including the current COVID-19 pandemic, the supply chain of filtering
facepiece respirators, such as N95 respirators, are disrupted. To combat shortages of N95 …

Nested PCR for rapid detection of mumps virus in cerebrospinal fluid from patients with neurological diseases

…, D Cisterna, MC Freire, J Cello - Journal of clinical …, 2000 - Am Soc Microbiol
In this study, we have developed a reverse transcription (RT)-nested polymerase chain reaction
(n-PCR) for the detection of mumps virus RNA in cerebrospinal fluid (CSF) from patients …

A study of the cellular immune response to enteroviruses in humans: identification of cross-reactive T cell epitopes on the structural proteins of enteroviruses

J Cello, Ö Strannegård… - Journal of general …, 1996 - microbiologyresearch.org
We have attempted to extend our understanding of the enteroviral cross-reactive T cell
response in humans. Peripheral blood mononuclear cells (PBMC) from healthy donors were …

Mac-1+ Cells Are the Predominant Subset in the Early Hepatic Lesions of Mice Infected with Francisella tularensis

JW Rasmussen, J Cello, H Gil, CA Forestal… - Infection and …, 2006 - Am Soc Microbiol
The cell composition of early hepatic lesions of experimental murine tularemia has not been
characterized with specific markers. The appearance of multiple granulomatous-necrotic …

Oncolytic poliovirus therapy and immunization with poliovirus-infected cell lysate induces potent antitumor immunity against neuroblastoma in vivo

H Toyoda, E Wimmer, J Cello - … journal of oncology, 2011 - spandidos-publications.com
In a previous study, we demonstrated that neuroblastoma subcutaneously implanted in
immuno-competent mice is eliminated by intratumoral administration of neuroattenuated …

[HTML][HTML] Cold-adapted viral attenuation (CAVA): highly temperature sensitive polioviruses as novel vaccine strains for a next generation inactivated poliovirus vaccine

…, JHHV Custers, H Schuitemaker, J Cello… - PLoS …, 2016 - journals.plos.org
The poliovirus vaccine field is moving towards novel vaccination strategies. Withdrawal of
the Oral Poliovirus Vaccine and implementation of the conventional Inactivated Poliovirus …