Poliovirus and poliomyelitis: a tale of guts, brains, and an accidental event
Nearly 100 years after its discovery poliovirus remains one of most thoroughly studied and
best understood virus models for the molecular virologist. While poliovirus has been of vital …
best understood virus models for the molecular virologist. While poliovirus has been of vital …
Chemical synthesis of poliovirus cDNA: generation of infectious virus in the absence of natural template
Full-length poliovirus complementary DNA (cDNA) was synthesized by assembling oligonucleotides
of plus and minus strand polarity. The synthetic poliovirus cDNA was transcribed by …
of plus and minus strand polarity. The synthetic poliovirus cDNA was transcribed by …
Oncolytic treatment and cure of neuroblastoma by a novel attenuated poliovirus in a novel poliovirus-susceptible animal model
Neuroblastoma is one of the most common solid tumors in children. Treatment is of limited
utility for high-risk neuroblastoma and prognosis is poor. Resistance of neuroblastoma to …
utility for high-risk neuroblastoma and prognosis is poor. Resistance of neuroblastoma to …
Mutation of a single conserved nucleotide between the cloverleaf and internal ribosome entry site attenuates poliovirus neurovirulence
The chemical synthesis of poliovirus (PV) cDNA combined with the cell-free synthesis of
infectious particles yielded virus whose mouse neurovirulence was highly attenuated (J. Cello, …
infectious particles yielded virus whose mouse neurovirulence was highly attenuated (J. Cello, …
[HTML][HTML] Dry heat sterilization as a method to recycle N95 respirator masks: The importance of fit
JG Yuen, AC Marshilok, PT Benziger, S Yan, J Cello… - PLoS …, 2022 - journals.plos.org
In times of crisis, including the current COVID-19 pandemic, the supply chain of filtering
facepiece respirators, such as N95 respirators, are disrupted. To combat shortages of N95 …
facepiece respirators, such as N95 respirators, are disrupted. To combat shortages of N95 …
Nested PCR for rapid detection of mumps virus in cerebrospinal fluid from patients with neurological diseases
…, D Cisterna, MC Freire, J Cello - Journal of clinical …, 2000 - Am Soc Microbiol
In this study, we have developed a reverse transcription (RT)-nested polymerase chain reaction
(n-PCR) for the detection of mumps virus RNA in cerebrospinal fluid (CSF) from patients …
(n-PCR) for the detection of mumps virus RNA in cerebrospinal fluid (CSF) from patients …
A study of the cellular immune response to enteroviruses in humans: identification of cross-reactive T cell epitopes on the structural proteins of enteroviruses
J Cello, Ö Strannegård… - Journal of general …, 1996 - microbiologyresearch.org
We have attempted to extend our understanding of the enteroviral cross-reactive T cell
response in humans. Peripheral blood mononuclear cells (PBMC) from healthy donors were …
response in humans. Peripheral blood mononuclear cells (PBMC) from healthy donors were …
Mac-1+ Cells Are the Predominant Subset in the Early Hepatic Lesions of Mice Infected with Francisella tularensis
JW Rasmussen, J Cello, H Gil, CA Forestal… - Infection and …, 2006 - Am Soc Microbiol
The cell composition of early hepatic lesions of experimental murine tularemia has not been
characterized with specific markers. The appearance of multiple granulomatous-necrotic …
characterized with specific markers. The appearance of multiple granulomatous-necrotic …
Oncolytic poliovirus therapy and immunization with poliovirus-infected cell lysate induces potent antitumor immunity against neuroblastoma in vivo
H Toyoda, E Wimmer, J Cello - … journal of oncology, 2011 - spandidos-publications.com
In a previous study, we demonstrated that neuroblastoma subcutaneously implanted in
immuno-competent mice is eliminated by intratumoral administration of neuroattenuated …
immuno-competent mice is eliminated by intratumoral administration of neuroattenuated …
[HTML][HTML] Cold-adapted viral attenuation (CAVA): highly temperature sensitive polioviruses as novel vaccine strains for a next generation inactivated poliovirus vaccine
…, JHHV Custers, H Schuitemaker, J Cello… - PLoS …, 2016 - journals.plos.org
The poliovirus vaccine field is moving towards novel vaccination strategies. Withdrawal of
the Oral Poliovirus Vaccine and implementation of the conventional Inactivated Poliovirus …
the Oral Poliovirus Vaccine and implementation of the conventional Inactivated Poliovirus …