Blood and lymphatic vessels form a versatile transport network and provide inductive signals
to regulate tissue-specific functions. Blood vessels in bone regulate osteogenesis and …

Blood vessels provide supportive microenvironments for maintaining tissue functions. Age-associated
vascular changes and their relation to tissue aging and pathology are poorly …

Angiogenesis is responsible for tissue vascularization during development, as well as in
pathological contexts, including cancer and ischemia. Vascular endothelial growth factors (…

Skeletal vasculature plays a central role in the maintenance of microenvironments for
osteogenesis and haematopoiesis. In addition to supplying oxygen and nutrients, vasculature …

Atrial natriuretic peptide (nppa/anf) and brain natriuretic peptide (nppb/bnp) form a gene cluster
with expression in the chambers of the developing heart. Despite restricted expression, a …

Genomic regulation of cardiomyocyte differentiation is central to heart development and
function. This study uses genetic loss-of-function human-induced pluripotent stem cell-derived …

The establishment of cardiac function in the developing embryo is essential to ensure blood
flow and, therefore, growth and survival of the animal. The molecular mechanisms …

The endocrine system consists of several highly vascularized glands that produce and
secrete hormones to maintain body homeostasis and regulate a range of bodily functions and …

High-resolution whole-organ imaging of cleared tissues captures cellular and molecular
insights within the intact tissue and tumour microenvironments. However, current …

This study establishes the homeodomain only protein, HOPX, as a determinant controlling the
molecular switch between cardiomyocyte progenitor and maturation gene programs. Time-…