Patient-derived xenografts (PDXs) are resected human tumors engrafted into mice for preclinical
studies and therapeutic testing. It has been proposed that the mouse host affects tumor …

Background Identification of chromosomal aneuploidies and copy number variants that are
associated with fetal structural anomalies has substantial value. Although whole-exome …

Objective The objective of the study is to investigate the experiences of couples who underwent
prenatal whole‐exome sequencing (WES) for fetal anomalies and the amount/type of …

Objectives To evaluate the concordance between DECT perfusion and ventilation/perfusion
(V/Q) scintigraphy in diagnosing chronic thromboembolic pulmonary hypertension (CTEPH). …

Short-read genome sequencing (GS) holds the promise of becoming the primary diagnostic
approach for the assessment of autism spectrum disorder (ASD) and fetal structural …

Background In the majority of cases, the cause of stillbirth remains unknown despite detailed
clinical and laboratory evaluation. Approximately 10 to 20% of stillbirths are attributed to …

Purpose To compare lung perfusion in PAH and pCTEPH on dual-energy CT (DECT)
examinations. Materials and methods Thirty-one patients with PAH (group 1; n = 19) and pCTEPH (…

This study reports a multilevel platform of gastric cancer PDXs and identifies a MSI gastric
signature that could contribute to the advancement of precision medicine in gastric cancer. …

Objectives To evaluate the frequency and pattern of pulmonary vascular abnormalities in
the year following COVID-19. Methods The study population included 79 patients remaining …

The Human Phenotype Ontology (HPO) is a widely used resource that comprehensively
organizes and defines the phenotypic features of human disease, enabling computational …