WashU Epigenome Browser ( https://epigenomegateway.wustl.edu/browser/ ) is a web-based
genomic data exploration tool that provides visualization, integration, and analysis of …

Previous urinary tract infections (UTIs) can predispose one to future infections; however, the
underlying mechanisms affecting recurrence are poorly understood. We previously found …

The recent derivation of human trophoblast stem cells (hTSCs) provides a scalable in vitro
model system of human placental development, but the molecular regulators of hTSC identity …

To the Editor—Three-dimensional (3D) genomic structures are vital for gene regulation and
cell function1. High-throughput technologies based on chromosome conformation capture …

Background Thoracic aortic aneurysms (TAAs) occur because of abnormal remodeling of
aortic extracellular matrix and are accompanied by the emergence of proteolytically active …

Genome browsers have become an intuitive and critical tool to visualize and analyze genomic
features and data. Conventional genome browsers display data/annotations on a single …

Recent advances in long-read sequencing technologies have not only dramatically increased
sequencing read length but also have improved the accuracy of detecting chemical …

Rationale: Thoracic aortic aneurysms (TAA) result from dysregulated remodeling of the
vascular extracellular matrix, and may occur as result of altered resident cellular phenotype. …

Colorectal cancer (CRC) is a biologically heterogeneous disease. To characterize its
mutational profile, we conduct targeted sequencing of 205 genes for 2,105 CRC cases with …

Hepatitis C virus (HCV) infection is a major cause of end-stage liver disease and hepatocellular
carcinoma. There have been rapid advances in HCV treatment with the development of …