Local connectivity and synaptic dynamics in mouse and human neocortex

…, L Kim, A Hoggarth, C Gamlin, S Ito, J Trinh… - Science, 2022 - science.org
We present a unique, extensive, and open synaptic physiology analysis platform and dataset.
Through its application, we reveal principles that relate cell type to synaptic properties and …

[PDF][PDF] Integrated morphoelectric and transcriptomic classification of cortical GABAergic cells

…, SM Sunkin, A Szafer, M Tieu, A Torkelson, J Trinh… - Cell, 2020 - cell.com
Neurons are frequently classified into distinct types on the basis of structural, physiological,
or genetic attributes. To better constrain the definition of neuronal cell types, we …

Scaled, high fidelity electrophysiological, morphological, and transcriptomic cell characterization

…, L Kim, R Mann, L Ng, A Oldre, R Rajanbabu, J Trinh… - Elife, 2021 - elifesciences.org
The Patch-seq approach is a powerful variation of the patch-clamp technique that allows for
the combined electrophysiological, morphological, and transcriptomic characterization of …

Genome‐wide analyses of Liberibacter species provides insights into evolution, phylogenetic relationships, and virulence factors

SP Thapa, A De Francesco, J Trinh… - Molecular plant …, 2020 - Wiley Online Library
‘Candidatus Liberibacter’ species are insect‐transmitted, phloem‐limited α‐Proteobacteria
in the order of Rhizobiales. The citrus industry is facing significant challenges due to …

[HTML][HTML] Human neocortical expansion involves glutamatergic neuron diversification

…, ER Thomsen, M Tieu, A Torkelson, J Trinh… - Nature, 2021 - nature.com
The neocortex is disproportionately expanded in human compared with mouse 1 , 2 , both
in its total volume relative to subcortical structures and in the proportion occupied by …

Sec-Delivered Effector 1 (SDE1) of 'Candidatus Liberibacter asiaticus' Promotes Citrus Huanglongbing

KJ Clark, Z Pang, J Trinh, N Wang… - Molecular Plant-Microbe …, 2020 - Am Phytopath Society
Sec-delivered effector 1 (SDE1) from the huanglongbing (HLB)-associated bacterium ‘Candidatus
Liberibacter asiaticus’ was previously characterized as an inhibitor of defense-related, …

Signature morphoelectric properties of diverse GABAergic interneurons in the human neocortex

…, I Szöts, N Taskin, B Thyagarajan, M Tieu, J Trinh… - Science, 2023 - science.org
Human cortex transcriptomic studies have revealed a hierarchical organization of γ-aminobutyric
acid–producing (GABAergic) neurons from subclasses to a high diversity of more …

Anti-Asian sentiment in the United States–COVID-19 and history

HA Chen, J Trinh, GP Yang - … Journal of Surgery, 2020 - americanjournalofsurgery.com
In 2020, the South Korean movie Parasite became the only foreign-language film to ever win
an Oscar for Best Picture. This historic first mirrors a broader trend towards acceptance and …

[HTML][HTML] Engineering Pseudomonas putida for efficient aromatic conversion to bioproduct using high throughput screening in a bioreactor

…, AK Lau, E Bowden, RA Herbert, J Trinh… - Metabolic …, 2021 - Elsevier
Pseudomonas putida KT2440 is an emerging biomanufacturing host amenable for use with
renewable carbon streams including aromatics such as para-coumarate. We used a pooled …

Morphoelectric and transcriptomic divergence of the layer 1 interneuron repertoire in human versus mouse neocortex

…, J Sandle, SM Sunkin, I Szots, M Tieu, M Toth, J Trinh… - Science, 2023 - science.org
Neocortical layer 1 (L1) is a site of convergence between pyramidal-neuron dendrites and
feedback axons where local inhibitory signaling can profoundly shape cortical processing. …