User profiles for Jessica Tyrrell
Jessica TyrrellVerified email at exeter.ac.uk Cited by 9583 |
Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry
More than one in three adults worldwide is either overweight or obese. Epidemiological studies
indicate that the location and distribution of excess fat, rather than general adiposity, are …
indicate that the location and distribution of excess fat, rather than general adiposity, are …
[HTML][HTML] Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms
Being a morning person is a behavioural indicator of a person’s underlying circadian rhythm.
Using genome-wide data from 697,828 UK Biobank and 23andMe participants we …
Using genome-wide data from 697,828 UK Biobank and 23andMe participants we …
[HTML][HTML] Genome-wide association study identifies genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates
Sleep is an essential state of decreased activity and alertness but molecular factors regulating
sleep duration remain unknown. Through genome-wide association analysis in 446,118 …
sleep duration remain unknown. Through genome-wide association analysis in 446,118 …
Genome-wide associations for birth weight and correlations with adult disease
Birth weight (BW) has been shown to be influenced by both fetal and maternal factors and in
observational studies is reproducibly associated with future risk of adult metabolic diseases …
observational studies is reproducibly associated with future risk of adult metabolic diseases …
Using human genetics to understand the disease impacts of testosterone in men and women
Testosterone supplementation is commonly used for its effects on sexual function, bone
health and body composition, yet its effects on disease outcomes are unknown. To better …
health and body composition, yet its effects on disease outcomes are unknown. To better …
Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors
Birth weight variation is influenced by fetal and maternal genetic and non-genetic factors,
and has been reproducibly associated with future cardio-metabolic health outcomes. In …
and has been reproducibly associated with future cardio-metabolic health outcomes. In …
[HTML][HTML] Genome-wide association analyses in 128,266 individuals identifies new morningness and sleep duration loci
Disrupted circadian rhythms and reduced sleep duration are associated with several human
diseases, particularly obesity and type 2 diabetes, but until recently, little was known about …
diseases, particularly obesity and type 2 diabetes, but until recently, little was known about …
Height, body mass index, and socioeconomic status: mendelian randomisation study in UK Biobank
Objective To determine whether height and body mass index (BMI) have a causal role in
five measures of socioeconomic status. Design Mendelian randomisation study to test for …
five measures of socioeconomic status. Design Mendelian randomisation study to test for …
[HTML][HTML] Genetic evidence for causal relationships between maternal obesity-related traits and birth weight
Importance Neonates born to overweight or obese women are larger and at higher risk of
birth complications. Many maternal obesity-related traits are observationally associated with …
birth complications. Many maternal obesity-related traits are observationally associated with …
Biological and clinical insights from genetics of insomnia symptoms
Insomnia is a common disorder linked with adverse long-term medical and psychiatric
outcomes. The underlying pathophysiological processes and causal relationships of insomnia …
outcomes. The underlying pathophysiological processes and causal relationships of insomnia …