The hippocampus is one of the most affected areas in Alzheimer’s disease (AD) 1. Moreover,
this structure hosts one of the most unique phenomena of the adult mammalian brain, …

Glycogen synthase kinase‐3β (GSK‐3β) has been postulated to mediate Alzheimer's disease
tau hyperphosphorylation, β‐amyloid‐induced neurotoxicity and presenilin‐1 mutation …

Tau is a microtubule-associated protein predominantly expressed in nerve cells that promote
microtubule assembly and microtubule stabilization. Tau is a cytosolic protein mainly …

Axonal regeneration in the lesioned mammalian central nervous system is abortive, and this
causes permanent disabilities in individuals with spinal cord injuries. In adult rats, olfactory …

Neurons, the basic information processing units of the nervous system, are characterized by
a complex polar morphology which is essential for their function. To attain their precise …

The failure of regenerating axons to grow within the adult mammalian central nervous system
(CNS) does not apply to the olfactory bulb (OB). In this structure, normal and transected …

Alzheimer disease (AD) is the most common form of age-related dementia. The etiology of
AD is considered to be multifactorial as only a negligible percentage of cases have a familial …

Glycogen synthase kinase3 (GSK3) is emerging as a prominent drug target in the CNS. The
most exciting of the possibilities of GSK3 lies within the treatment of Alzheimer's disease (AD…

Deregulation of glycogen synthase kinase‐3 (GSK‐3) activity in neurones has been postulated
as a key feature in Alzheimer's disease (AD) pathogenesis. This was further supported by …

Glycogen synthase kinase‐3 (GSK‐3) is a serine/threonine kinase regulating diverse cellular
functions including metabolism, transcription and cell survival. Numerous intracellular …