Pyroptosis is a form of regulated cell death mediated by gasdermin family members, among
which the function of GSDMC has not been clearly described. Herein, we demonstrate that …

Iron has been shown to trigger oxidative stress by elevating reactive oxygen species (ROS)
and to participate in different modes of cell death, such as ferroptosis, apoptosis and …

Breast cancer (BC) patients in China suffered from a variety of psychology stress such as
perceived stress and anxiety, posttraumatic growth (PTG) as a positive factor could promote …

Gluconeogenesis, an essential metabolic process for hepatocytes, is downregulated in
hepatocellular carcinoma (HCC). Here we show that the nuclear receptor Nur77 is a tumour …

Background The immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection in COVID-19 patients has been extensively investigated. However, …

Low well-being is common among Chinese pregnant women but few effective interventions
currently exist to improve prenatal stress and negative emotions. Mindfulness-based stress …

Despite early clinical successes, the mechanisms of action of low-dose interleukin-2 (LD-IL-2)
immunotherapy remain only partly understood. Here we examine the effects of interval …

Background With the development of positive psychology, posttraumatic growth research on
cancer patients has attracted increasing attention from researchers. It is immensely …

Driven by the necessity to survive environmental pathogens, the human immune system
has evolved exceptional diversity and plasticity, to which several factors contribute including …

Functional polymeric drug delivery systems have generated enormous interest due to their
excellent features. This paper reports the development of a novel pH and redox dual-…