High-frequency disease-causing alleles exist, but their number is rather small. This study
aimed to interpret and reclassify common pathogenic (P) and likely pathogenic (LP) variants in …

Vascular cambium, a lateral plant meristem, is a central producer of woody biomass.
Although a few transcription factors have been shown to regulate cambial activity 1 , the …

… Jiale Xiang and Jiguang Peng contributed equally to this work. … Jiale Xiang, Jiguang Peng,
and Zhiyu Peng were employed at BGI Genomics at the time of submission. No other conflicts …

Purpose The benefits of concurrent newborn hearing and genetic screening have not been
statistically proven due to limited sample sizes and outcome data. To fill this gap, we …

Through the molecular isomerization strategy, three simple nonfused electron acceptors (AOT1,
AOT2, and AOT3) are synthesized by altering the position of the isooctyloxy group on …

The cost-effective organic semiconductors are strongly needed in organic photovoltaics (OPVs).
Herein, two medium bandgap (MBG) electron acceptors, TPT4F and TPT4Cl are …

Importance Newborn screening via biochemical tests is in use worldwide. The availability of
genetic sequencing has allowed rapid screening for a substantial number of monogenic …

Newborn hearing screening is not designed to detect delayed-onset prelingual hearing loss
or aminoglycoside-antibiotic-induced ototoxicity. Cases with severe to profound hearing …

BACKGROUND Genome-wide noninvasive prenatal testing identifies several rare autosomal
trisomies in the general obstetrical population, but its use is questioned by its low positive …

Expanded carrier screening (ECS) has been demonstrated to increase the detection rate of
carriers compared with traditional tests. The aim of this study was to assess the potential …