We have identified a novel zinc finger-containing transcription factor, called Osterix (Osx),
that is specifically expressed in all developing bones. In Osx null mice, no bone formation …

Chondrogenesis results in the formation of cartilages, initial skeletal elements that can
serve as templates for endochondral bone formation. Cartilage formation begins with the …

The liver and exocrine pancreas share a common structure, with functioning units (hepatic
plates and pancreatic acini) connected to the ductal tree. Here we show that Sox9 is …

Chondrogenesis is a multistep process that is essential for endochondral bone formation.
Previous results have indicated a role for β-catenin and Wnt signaling in this pathway. Here we …

L-Sox5 and Sox6 are highly identical Sry-related transcription factors coexpressed in cartilage.
Whereas Sox5 and Sox6 single null mice are born with mild skeletal abnormalities, Sox5; …

In humans, SOX9 heterozygous mutations cause the severe skeletal dysmorphology
syndrome campomelic dysplasia. Except for clinical descriptions, little is known about the …

The transcription factor Sox9 is expressed in all chondroprogenitors and has an essential
role in chondrogenesis. Sox9 is also expressed in other tissues, including central nervous …

The terminal t-loop structure adopted by mammalian telomeres is thought to prevent telomeres
from being recognized as double-stranded DNA breaks by sequestering the 3′ single-…

Dear Editor, Coronavirus disease 2019 (COVID-19) caused by the novel severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) 1 has resulted in over 13 million confirmed …

Background Observational studies suggest that shift work may be associated with diabetes
mellitus (DM). However, the results are inconsistent. No systematic reviews have applied …