Microbial electrosynthesis, a process in which microorganisms use electrons derived from
electrodes to reduce carbon dioxide to multicarbon, extracellular organic compounds, is a …

Stem cells undergo dynamic changes in response to injury to regenerate lost cells. However,
the identity of transitional states and the mechanisms that drive their trajectories remain …

Most colorectal cancers (CRCs) containing activated BRAF (BRAF[V600E]) have a CpG island
methylator phenotype (CIMP) characterized by aberrant hypermethylation of many genes, …

The Tead family transcription factors are the major intracellular mediators of the Hippo-Yap
pathway. Despite the importance of Hippo signaling in tumorigenesis, Tead-dependent …

Inactivation of the RB1 tumor suppressor gene is common in several types of therapy-resistant
cancers, including metastatic castration-resistant prostate cancer, and predicts poor …

Regeneration is a complex chain of events that restores a tissue to its original size and
shape. The tissue-wide coordination of cellular dynamics that is needed for proper …

Background ATAC-seq (Assays for Transposase-Accessible Chromatin using sequencing)
is a recently developed technique for genome-wide analysis of chromatin accessibility. …

The TRIM37 (also known as MUL) gene is located in the 17q23 chromosomal region, which
is amplified in up to ∼40% of breast cancers 1 . TRIM37 contains a RING finger domain, a …

To the Editor—As high-throughput sequencing’s cost continues to decrease and its applications
continue to grow, the amount of data and the number of data types produced by this …

This study suggests that ssDNA replication gaps are fundamental to the toxicity of genotoxic
agents and underlie the BRCA-cancer phenotype “BRCAness,” yielding promising …