[HTML][HTML] The PI3K/AKT pathway in obesity and type 2 diabetes

X Huang, G Liu, J Guo, Z Su - International journal of biological …, 2018 - ncbi.nlm.nih.gov
Obesity and type 2 diabetes mellitus are complicated metabolic diseases that affect multiple
organs and are characterized by hyperglycaemia. Currently, stable and effective treatments …

M2b macrophage polarization and its roles in diseases

…, S Zhang, H Wu, X Rong, J Guo - Journal of leukocyte …, 2019 - academic.oup.com
Macrophages play an important role in a wide variety of physiologic and pathologic
processes. Plasticity and functional polarization are hallmarks of macrophages. Macrophages …

Network pharmacology in research of Chinese medicine formula: methodology, application and prospective

T Luo, Y Lu, S Yan, X Xiao, X Rong, J Guo - Chinese journal of integrative …, 2020 - Springer
Chinese medicine (CM) is usually prescribed as CM formula to treat disease. The lack of
effective research approach makes it difficult to elucidate the molecular mechanisms of CM …

[PDF][PDF] Association of blood glucose control and outcomes in patients with COVID-19 and pre-existing type 2 diabetes

…, G Peng, P Ye, J Yang, Y Yuan, X Huang, J Guo… - Cell metabolism, 2020 - cell.com
Type 2 diabetes (T2D) is a major comorbidity of COVID-19. However, the impact of blood
glucose (BG) control on the degree of required medical interventions and on mortality in …

[PDF][PDF] In-hospital use of statins is associated with a reduced risk of mortality among individuals with COVID-19

…, PP Liu, R Loomba, YX Ji, J Xia, Y Wang, J Cai, J Guo… - Cell metabolism, 2020 - cell.com
Statins are lipid-lowering therapeutics with favorable anti-inflammatory profiles and have
been proposed as an adjunct therapy for COVID-19. However, statins may increase the risk of …

Mechanically strong, flexible polyimide aerogels cross-linked with aromatic triamine

…, D Quade, SL Vivod, H Guo, J Guo… - … applied materials & …, 2012 - ACS Publications
Polyimide gels are produced by cross-linking anhydride capped polyamic acid oligomers
with aromatic triamine in solution and chemically imidizing. The gels are then supercritically …

Polyimide aerogels cross-linked through amine functionalized polyoligomeric silsesquioxane

H Guo, MAB Meador, L McCorkle… - … applied materials & …, 2011 - ACS Publications
We report the first synthesis of polyimide aerogels cross-linked through a polyhedral oligomeric
silsesquioxane, octa(aminophenyl)silsesquioxane (OAPS). Gels formed from polyamic …

Lung transplantation as therapeutic option in acute respiratory distress syndrome for coronavirus disease 2019-related pulmonary fibrosis

JY Chen, K Qiao, F Liu, B Wu, X Xu, GQ Jiao… - Chinese medical …, 2020 - mednexus.org
Background: Critical patients with the coronavirus disease 2019 (COVID-19), even those
whose nucleic acid test results had turned negative and those receiving maximal medical …

Advances in understanding the interrelations between leptin resistance and obesity

H Pan, J Guo, Z Su - Physiology & behavior, 2014 - Elsevier
Obesity, which has developed into a global epidemic, is a risk factor in most chronic diseases
and some forms of malignancy. The discovery of leptin in 1994 has opened a new field in …

[PDF][PDF] Gut microbiome fermentation determines the efficacy of exercise for diabetes prevention

…, CKY Cheung, KSL Lam, Y Wang, Z Xia, D Ye, J Guo… - Cell Metabolism, 2020 - cell.com
Exercise is an effective strategy for diabetes management but is limited by the phenomenon
of exercise resistance (ie, the lack of or the adverse response to exercise on metabolic …