User profiles for Jiaying Zheng
Jiaying Zheng (Fiona)mayo clinic Verified email at mayo.edu Cited by 985 |
Neuronal network activity controls microglial process surveillance in awake mice via norepinephrine signaling
Microglia dynamically survey the brain parenchyma. Microglial processes interact with
neuronal elements; however, what role neuronal network activity plays in regulating microglial …
neuronal elements; however, what role neuronal network activity plays in regulating microglial …
[HTML][HTML] Faecal microbiome-based machine learning for multi-class disease diagnosis
…, W Tang, L Zhang, JQY Liang, YK Yau, J Zheng… - Nature …, 2022 - nature.com
Systemic characterisation of the human faecal microbiome provides the opportunity to develop
non-invasive approaches in the diagnosis of a major human disease. However, shared …
non-invasive approaches in the diagnosis of a major human disease. However, shared …
[PDF][PDF] Alzheimer's risk factors age, APOE genotype, and sex drive distinct molecular pathways
Evidence suggests interplay among the three major risk factors for Alzheimer's disease (AD):
age, APOE genotype, and sex. Here, we present comprehensive datasets and analyses of …
age, APOE genotype, and sex. Here, we present comprehensive datasets and analyses of …
Elevating microglia TREM2 reduces amyloid seeding and suppresses disease-associated microglia
TREM2 is exclusively expressed by microglia in the brain and is strongly linked to the risk for
Alzheimer’s disease (AD). As microglial responses modulated by TREM2 are central to AD …
Alzheimer’s disease (AD). As microglial responses modulated by TREM2 are central to AD …
Chemogenetic manipulation of microglia inhibits neuroinflammation and neuropathic pain in mice
Microglia play an important role in the central sensitization and chronic pain. However, a
direct connection between microglial function and pain development in vivo remains …
direct connection between microglial function and pain development in vivo remains …
APOE4 exacerbates α-synuclein pathology and related toxicity independent of amyloid
The apolipoprotein E (APOE) ε4 allele is the strongest genetic risk factor for late-onset
Alzheimer’s disease mainly by driving amyloid-β pathology. Recently, APOE4 has also been …
Alzheimer’s disease mainly by driving amyloid-β pathology. Recently, APOE4 has also been …
Microglia enhance post-anesthesia neuronal activity by shielding inhibitory synapses
Microglia are resident immune cells of the central nervous system and play key roles in brain
homeostasis. During anesthesia, microglia increase their dynamic process surveillance …
homeostasis. During anesthesia, microglia increase their dynamic process surveillance …
The complement C3‐C3aR pathway mediates microglia–astrocyte interaction following status epilepticus
Gliosis is a histopathological characteristic of epilepsy that comprises activated microglia and
astrocytes. It is unclear whether or how crosstalk occurs between microglia and astrocytes …
astrocytes. It is unclear whether or how crosstalk occurs between microglia and astrocytes …
Exogenous foliar application of fulvic acid alleviate cadmium toxicity in lettuce (Lactuca sativa L.)
Y Wang, R Yang, J Zheng, Z Shen, X Xu - … and environmental safety, 2019 - Elsevier
It was reported that fulvic acid (FA) has a positive effect on enhancing plant tolerance to various
environmental stresses, including salinity stress and drought stress and so on. However, …
environmental stresses, including salinity stress and drought stress and so on. However, …
[HTML][HTML] VEGF-A in serum protects against memory impairment in APP/PS1 transgenic mice by blocking neutrophil infiltration
…, Q Wang, Y Xie, L Tan, Y Yang, X Zhang, J Zheng… - Molecular …, 2023 - nature.com
Activation of innate immunity in the brain is a prominent feature of Alzheimer’s disease (AD).
The present study investigated the regulation of innate immunity by wild-type serum …
The present study investigated the regulation of innate immunity by wild-type serum …